Mississippi Poison Control Center, Department of Emergency Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA.
Clin Toxicol (Phila). 2011 Mar;49(3):167-70. doi: 10.3109/15563650.2011.559473.
Monosodium methanearsonate (MSMA) is an organo-arsenic containing herbicide. There is scant information available concerning the toxicity of this chemical in humans.
Seven male teenagers, 15-18 years of age, inadvertently used a MSMA herbicide as cooking oil to fry fish. All had early gastrointestinal (GI) symptoms. Whole blood arsenic concentrations ranged from 348 to 613 μg/L and initial urine levels ranged from 81 400 to 226 300 μg-arsenic/g-creatinine. They were all treated with dimercaprol for 1 day and succimer for 19 days. They were followed for 15-months and had no evidence of any serious toxicity.
MSMA produces early GI symptoms and very high levels of arsenic in blood and urine, but no evidence of long-term toxicity.
甲亚砷酸钠(MSMA)是一种含有机砷的除草剂。关于这种化学物质在人类体内的毒性,目前可用的信息很少。
七名 15-18 岁的男性青少年不慎将 MSMA 除草剂当作食用油来炸鱼。所有人都出现了早期胃肠道(GI)症状。全血砷浓度范围为 348 至 613μg/L,初始尿砷水平范围为 81400 至 226300μg-砷/g-肌酐。他们均接受二巯丙醇治疗 1 天和二巯丁二酸治疗 19 天。对他们进行了 15 个月的随访,没有任何严重毒性的证据。
MSMA 会引起早期胃肠道症状以及血液和尿液中非常高的砷含量,但没有长期毒性的证据。