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误食单钠甲砷酸盐导致 7 名青少年中毒。

Inadvertent poisoning of seven teenagers with monosodium methanearsonate.

机构信息

Mississippi Poison Control Center, Department of Emergency Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA.

出版信息

Clin Toxicol (Phila). 2011 Mar;49(3):167-70. doi: 10.3109/15563650.2011.559473.

DOI:10.3109/15563650.2011.559473
PMID:21495885
Abstract

INTRODUCTION

Monosodium methanearsonate (MSMA) is an organo-arsenic containing herbicide. There is scant information available concerning the toxicity of this chemical in humans.

CASE REPORT

Seven male teenagers, 15-18 years of age, inadvertently used a MSMA herbicide as cooking oil to fry fish. All had early gastrointestinal (GI) symptoms. Whole blood arsenic concentrations ranged from 348 to 613 μg/L and initial urine levels ranged from 81 400 to 226 300 μg-arsenic/g-creatinine. They were all treated with dimercaprol for 1 day and succimer for 19 days. They were followed for 15-months and had no evidence of any serious toxicity.

CONCLUSION

MSMA produces early GI symptoms and very high levels of arsenic in blood and urine, but no evidence of long-term toxicity.

摘要

简介

甲亚砷酸钠(MSMA)是一种含有机砷的除草剂。关于这种化学物质在人类体内的毒性,目前可用的信息很少。

病例报告

七名 15-18 岁的男性青少年不慎将 MSMA 除草剂当作食用油来炸鱼。所有人都出现了早期胃肠道(GI)症状。全血砷浓度范围为 348 至 613μg/L,初始尿砷水平范围为 81400 至 226300μg-砷/g-肌酐。他们均接受二巯丙醇治疗 1 天和二巯丁二酸治疗 19 天。对他们进行了 15 个月的随访,没有任何严重毒性的证据。

结论

MSMA 会引起早期胃肠道症状以及血液和尿液中非常高的砷含量,但没有长期毒性的证据。

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