Department of Anesthesiology and Pain Medicine, Dongguk University College of Medicine, Ilsandong-gu,Goyang, 410-773, South Korea.
J Clin Anesth. 2011 May;23(3):227-30. doi: 10.1016/j.jclinane.2010.01.008. Epub 2011 Apr 15.
Sick sinus syndrome is caused by sinus node dysfunction that renders it unable to function as a pacemaker. Patients with sick sinus syndrome are often asymptomatic or have symptoms that are mild and nonspecific. Lidocaine (0.5 mg/kg) injection is used for reduction of pain associated with intravenous injection of propofol. Episodes of marked bradycardia with sinus arrest after prophylactic lidocaine injection are reported in a 69-y-old man with no apparent preoperative cardiac disease or electrocardiographic abnormality. Surgery was postponed, and he was later diagnosed with sick sinus syndrome.
病窦综合征是由窦房结功能障碍引起的,使其无法作为起搏器发挥功能。病窦综合征患者通常无症状或症状轻微且非特异性。利多卡因(0.5mg/kg)注射用于减轻异丙酚静脉注射引起的疼痛。在一例无明显术前心脏病或心电图异常的 69 岁男性中,预防性利多卡因注射后出现明显心动过缓伴窦性停搏。手术被推迟,后来他被诊断为病窦综合征。