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在无症状病态窦房结综合征患者麻醉诱导期间,利多卡因引起严重心动过缓。

Profound bradycardia with lidocaine during anesthesia induction in a silent sick sinus syndrome patient.

机构信息

Department of Anesthesiology and Pain Medicine, Dongguk University College of Medicine, Ilsandong-gu,Goyang, 410-773, South Korea.

出版信息

J Clin Anesth. 2011 May;23(3):227-30. doi: 10.1016/j.jclinane.2010.01.008. Epub 2011 Apr 15.

Abstract

Sick sinus syndrome is caused by sinus node dysfunction that renders it unable to function as a pacemaker. Patients with sick sinus syndrome are often asymptomatic or have symptoms that are mild and nonspecific. Lidocaine (0.5 mg/kg) injection is used for reduction of pain associated with intravenous injection of propofol. Episodes of marked bradycardia with sinus arrest after prophylactic lidocaine injection are reported in a 69-y-old man with no apparent preoperative cardiac disease or electrocardiographic abnormality. Surgery was postponed, and he was later diagnosed with sick sinus syndrome.

摘要

病窦综合征是由窦房结功能障碍引起的,使其无法作为起搏器发挥功能。病窦综合征患者通常无症状或症状轻微且非特异性。利多卡因(0.5mg/kg)注射用于减轻异丙酚静脉注射引起的疼痛。在一例无明显术前心脏病或心电图异常的 69 岁男性中,预防性利多卡因注射后出现明显心动过缓伴窦性停搏。手术被推迟,后来他被诊断为病窦综合征。

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