孕甾类药物Althesin对癫痫病理生理学的作用。
Contribution of pregnan steroid Althesin to the pathophysiology of epilepsy.
作者信息
Nádvorník P, Kolarík J, Drlicková V
机构信息
Research Institute of Higher Nervous Activity, Palacký University, Olomouc, Czechoslovakia.
出版信息
Acta Univ Palacki Olomuc Fac Med. 1990;128:17-21.
PMID:2149796
Abstract
The original study with Althesin in the development of epilepsy was carried out in nine patients. EEG and SEEG records show that sensitivity to Althesin, which is a mixture of pregnandiol and pregnan acetate, precursors of sexual hormones, raises in the direction to the oldest brain formations. A physiological substance in provoking epilepsy was discovered.
摘要
最初关于阿尔泰辛（Althesin）在癫痫研究中的实验是在9名患者身上进行的。脑电图（EEG）和深部脑电图（SEEG）记录显示，对阿尔泰辛（一种孕二醇和孕烷醋酸酯的混合物，即性激素的前体）的敏感性，随着脑结构年龄的增长而增加。一种引发癫痫的生理物质被发现了。
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