Department of Water Resources and Environmental Engineering, Tamkang University, Taipei, Taiwan.
ASAIO J. 2011 May-Jun;57(3):188-96. doi: 10.1097/MAT.0b013e318213f9c2.
Design limitations of current mechanical heart valves cause blood flow to separate at the leaflet edges and annular valve base, forming downstream vortex mixing and high turbulent shear stresses. The closing behavior of a bileaflet valve is associated with reverse flow and may lead to cavitation phenomenon. The new trileaflet (TRI) design opens similar to a physiologic valve with central flow and closes primarily due to the vortices in the aortic sinus. In this study, we measured the St. Jude Medical 27 mm and the TRI 27 mm valves in the aortic position of a pulsatile circulatory mock loop under physiologic conditions with digital particle image velocimetry (DPIV). Our results showed the major principal Reynolds shear stresses were <100 N/m2 for both valves, and turbulent viscous shear stresses were smaller than 15 N/m2. The TRI valve closed more slowly than the St. Jude Medical valve. As the magnitudes of the shear stresses were similar, the closing velocity of the valves should be considered as an important factor and might reduce the risks of thrombosis and thromboembolism.
目前的机械心脏瓣膜的设计局限性导致血流在瓣叶边缘和环形瓣膜基座处分离,形成下游涡流混合和高湍流剪切应力。双叶瓣的关闭行为与反流有关,可能导致空化现象。新的三叶瓣(TRI)设计类似于具有中心流的生理瓣膜打开,并主要由于主动脉窦中的涡流而关闭。在这项研究中,我们在脉动循环模拟回路的主动脉位置下,在生理条件下使用数字粒子图像测速法(DPIV)测量了 St. Jude Medical 27mm 和 TRI 27mm 瓣膜。我们的结果表明,两个瓣膜的主要主雷诺剪切应力均<100 N/m2,而湍流粘性剪切应力均小于 15 N/m2。TRI 瓣关闭速度比 St. Jude Medical 瓣慢。由于剪切应力的大小相似,瓣膜的关闭速度应被视为一个重要因素,可能会降低血栓形成和血栓栓塞的风险。