Division of Women and Child Health, The Aga Khan University, Stadium Road, PO Box 3500, Karachi 74800, Pakistan.
BMC Public Health. 2011 Apr 13;11 Suppl 3(Suppl 3):S7. doi: 10.1186/1471-2458-11-S3-S7.
Of the global burden of 2.6 million stillbirths, around 1.2 million occur during labour i.e. are intrapartum deaths. In low-/middle-income countries, a significant proportion of women give birth at home, usually in the absence of a skilled birth attendant. This review discusses the impact of skilled birth attendance (SBA) and the provision of Emergency Obstetric Care (EOC) on stillbirths and perinatal mortality.
A systematic literature search was performed on PubMed/MEDLINE, Cochrane Database and the WHO regional libraries. Data of all eligible studies were extracted into a standardized Excel sheet containing variables such as participants' characteristics, sample size, location, setting, blinding, allocation concealment, intervention and control details and limitations. We undertook a meta-analysis of the impact of SBA on stillbirths. Given the paucity of data from randomized trials or robust quasi-experimental designs, we undertook an expert Delphi consultation to determine impact estimates of provision of Basic and Comprehensive EOC on reducing stillbirths if there would be universal coverage (99%).
The literature search yielded 871 hits. A total of 21 studies were selected for data abstraction. Our meta-analysis on community-based skilled birth attendance based on two before-after studies showed a 23% significant reduction in stillbirths (RR = 0.77; 95% CI: 0.69 - 0.85). The overall quality grade of available evidence for this intervention on stillbirths was 'moderate'. The Delphi process supported the estimated reduction in stillbirths by skilled attendance and experts further suggested that the provision of Basic EOC had the potential to avert intrapartum stillbirths by 45% and with provision of Comprehensive EOC this could be reduced by 75%. These estimates are conservative, consistent with historical trends in maternal and perinatal mortality from both developed and developing countries, and are recommended for inclusion in the Lives Saved Tool (LiST) model.
Both Skilled Birth Attendance and Emergency/or Essential Obstetric Care have the potential to reduce the number of stillbirths seen globally. Further evidence is needed to be able to calculate an effect size.
在全球 260 万例死产中,约有 120 万例发生在分娩期间,即产时死亡。在中低收入国家,相当一部分妇女在家中分娩,通常没有熟练的接生员。本综述讨论了熟练接生(SBA)和提供紧急产科护理(EOC)对死产和围产儿死亡的影响。
对 PubMed/MEDLINE、Cochrane 数据库和世卫组织区域图书馆进行了系统文献检索。将所有合格研究的数据提取到一个标准化的 Excel 表格中,其中包含参与者特征、样本量、地点、环境、盲法、分配隐藏、干预和对照细节以及局限性等变量。我们对 SBA 对死产的影响进行了荟萃分析。鉴于随机试验或稳健准实验设计的数据稀缺,我们进行了专家德尔菲咨询,以确定如果普遍覆盖(99%),提供基本和综合 EOC 对降低死产的影响估计。
文献检索产生了 871 个结果。共有 21 项研究被选中进行数据提取。我们对基于两项前后对照研究的社区为基础的熟练接生进行的荟萃分析显示,死产率显著降低了 23%(RR=0.77;95%CI:0.69-0.85)。现有证据对这项干预措施在死产方面的总体质量等级为“中等”。德尔菲过程支持熟练接生减少死产的估计,专家们进一步建议,提供基本产科护理有可能将产时死产减少 45%,而提供全面产科护理则可减少 75%。这些估计是保守的,与发达国家和发展中国家的孕产妇和围产儿死亡率的历史趋势一致,建议将其纳入挽救生命工具(LiST)模型。
熟练接生和紧急/基本产科护理都有可能减少全球范围内的死产数量。需要进一步的证据来计算效果大小。