Cline H T, Debski E A, Constantine-Paton M
Department of Biology, Yale University, New Haven, CT 06511.
Adv Exp Med Biol. 1990;268:197-203. doi: 10.1007/978-1-4684-5769-8_23.
The importance of patterned retinal activity in visual system development has been recognized since Hubel and Wiesels early experiments (1963). The NMDA receptor is one cellular mechanism which can recognize patterned retinal activity and convey an intracellular message of that activity. It will now be of considerable interest to elucidate the cellular events involved in synapse stabilization subsequent to NMDA receptor activation.
自休伯尔和威塞尔早期实验(1963年)以来,视网膜模式化活动在视觉系统发育中的重要性已得到认可。N-甲基-D-天冬氨酸(NMDA)受体是一种能够识别视网膜模式化活动并传递该活动细胞内信息的细胞机制。阐明NMDA受体激活后参与突触稳定的细胞事件现在将具有相当大的意义。