Wakui Noritaka, Takayama Ryuji, Mimura Takahiko, Kamiyama Naohisa, Maruyama Kenichi, Sumino Yasukiyo
Division of Gastroenterology and Hepatology, Toho University Omori Medical Center, Tokyo, Japan.
Case Rep Gastroenterol. 2011 Mar 26;5(1):100-9. doi: 10.1159/000326951.
Chronic heavy consumption of alcohol is associated with increased risks of developing liver cirrhosis, hepatocellular carcinoma, and esophageal varices. Cessation of alcohol consumption is the most important requirement in treating these diseases. However, judging whether patients have actually maintained abstinence from alcohol requires reliance on their reports, which vary substantially across individuals using the test methods currently available. Arrival time parametric imaging (At-PI) using Sonazoid-enhanced ultrasonography is regarded as a useful approach for assessing the progression of lesions that have developed in liver parenchyma. In this study, we report two cases for whom this approach was successfully applied to indicate the drinking status of a heavy drinker. At-PI enables approximate and objective assessment of the drinking status of patients, independent of their reports; therefore, it is a promising method for providing information about drinking status.
长期大量饮酒会增加患肝硬化、肝细胞癌和食管静脉曲张的风险。戒酒是治疗这些疾病的最重要要求。然而,判断患者是否真正戒酒需要依靠他们的报告,而使用目前可用的检测方法,这些报告在个体之间差异很大。使用声诺维增强超声的到达时间参数成像(At-PI)被认为是评估肝实质中已发生病变进展的一种有用方法。在本研究中,我们报告了两例成功应用该方法来指示重度饮酒者饮酒状态的病例。At-PI能够独立于患者报告对其饮酒状态进行大致客观的评估;因此,它是一种提供饮酒状态信息的有前景的方法。