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低收入国家高血压的流行病学:乌干达农村基于人群的横断面调查。

Epidemiology of hypertension in low-income countries: a cross-sectional population-based survey in rural Uganda.

机构信息

Medical Research Council/Uganda Virus Research Institute (MRC/UVRI) Uganda Research Unit on AIDS, Entebbe, Uganda.

出版信息

J Hypertens. 2011 Jun;29(6):1061-8. doi: 10.1097/HJH.0b013e3283466e90.

Abstract

OBJECTIVE

Population-based data on burden of hypertension are crucial for planning and implementation of prevention and control strategies but are often limited in developing countries in Africa. We assessed the prevalence of hypertension and related risk factors in a population cohort in rural Uganda initially established for HIV surveys.

METHODS

In a cross-sectional population-based survey of hypertension and related risk factors in 2009, trained field staff administered a questionnaire and obtained a single measurement of blood pressure, BMI, waist and hip circumference, waist/hip ratio (WHR) and random plasma glucose. All members of the population cohort aged 13 years and above were eligible for survey participation. Logistic regression was used to evaluate factors associated with high blood pressure, defined as SBP (mmHg) ≥ 140 or DBP ≥ 90.

RESULTS

Of the 4801 men and 5372 women who were eligible, 2719 (56.6%) men and 3959 (73.7%) women participated in the survey. The prevalence of high blood pressure was 22.0%, age standardized to the local population. Factors that were independently associated with high blood pressure were increasing age, BMI and elevated glucose in both sexes, extremes of education level (none and secondary or above) among men, and being unmarried and waist circumference ≥ 80 cm among women. Levels of reported hypertension were very low, with nine out 10 people unaware of their condition.

CONCLUSION

The use of established research infrastructure, for example, community HIV surveys, can help to generate the population-based data on the prevalence of hypertension and related risk factors needed to inform planning and implementation of effective prevention and control strategies in low-income countries. There is an urgent need to strengthen health services in responding effectively to the large burden of undetected hypertension.

摘要

目的

基于人群的高血压负担数据对于规划和实施预防与控制策略至关重要,但在非洲的发展中国家往往较为有限。我们评估了乌干达农村一个最初为艾滋病毒调查而建立的人群队列中高血压及相关危险因素的流行情况。

方法

在 2009 年进行的高血压及相关危险因素的横断面人群调查中,经过培训的现场工作人员会进行问卷调查,并对血压、体重指数(BMI)、腰围和臀围、腰臀比(WHR)和随机血浆葡萄糖进行单次测量。所有年龄在 13 岁及以上的人群队列成员都有资格参与调查。使用逻辑回归评估与高血压相关的因素,高血压定义为收缩压(mmHg)≥140 或舒张压≥90。

结果

在 4801 名男性和 5372 名女性中,有 2719 名(56.6%)男性和 3959 名(73.7%)女性参与了调查。高血压的患病率为 22.0%,按当地人口年龄标准化。与高血压独立相关的因素是年龄增长、男女两性的 BMI 和血糖升高、男性中教育程度处于极端(无教育或中等以上)以及女性中未婚和腰围≥80cm。报告的高血压水平非常低,十分之九的人不知道自己的病情。

结论

利用现有的研究基础设施,例如社区艾滋病毒调查,可以帮助生成基于人群的高血压流行情况和相关危险因素数据,为低收入国家规划和实施有效的预防与控制策略提供信息。迫切需要加强卫生服务,以有效应对未被发现的高血压的巨大负担。

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