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穆拉戈医院急诊科高血压危象的患病率、模式及相关因素;一项横断面研究。

Prevalence, patterns and factors associated with hypertensive crises in Mulago hospital emergency department; a cross-sectional study.

作者信息

Nakalema Irene, Kaddumukasa Mark, Nakibuuka Jane, Okello Emmy, Sajatovic Martha, Katabira Elly

机构信息

Department of Medicine, College of Health Sciences Makerere University, P. O. Box 7072 Kampala, Uganda.

Mulago National Referral and Teaching Hospital, P.O Box 7051 Kampala, Uganda.

出版信息

Afr Health Sci. 2019 Mar;19(1):1757-1767. doi: 10.4314/ahs.v19i1.52.

Abstract

BACKGROUND

Hypertension is increasing in sub-Saharan Africa (SSA) and it's the single most important modifiable stroke risk factor, yet it's control is not routinely emphasized.The prevalence, pattern and factors associated with hypertensive urgencies and emergencies in Uganda is not well established. A cross-sectional study, was conducted between November 2015 and February 2016, using a complete clinical examination and pre-tested standardized questionnaire subjects were enrolled. The prevalence of hypertensive crises and associations of demographic and clinical factors determined using logistic regression.

RESULTS

The prevalence of hypertensive crises was 5.1%, (203/4000) of all admissions at the medical section of the accident and emergency ward of Mulago National Referral Hospital. The hypertensive urgencies and emergencies accounted for 32.5% and 67.5% respectively among study subjects with hypertension. Among those with hypertensive crises, 41.1% were aged 45-65 years and half were female. Self-reported compliance was significantly different between those with hypertensive crisis compared to non-hypertensive crisis with OR; (95% CI) 52.4; (24.5 - 111.7), p-value =<0.001. Acute stroke was the commonest hypertensive emergency.

CONCLUSION

Hypertensive emergencies are common and significantly associated with poor compliance to prescribed anti-hypertensive drugs. Acute stroke is the commonest presentation in our setting.

摘要

背景

高血压在撒哈拉以南非洲地区(SSA)呈上升趋势,它是最重要的可改变的中风风险因素,但对其控制并未得到常规重视。乌干达高血压急症和紧急情况的患病率、模式及相关因素尚不明确。2015年11月至2016年2月进行了一项横断面研究,采用完整的临床检查和预先测试的标准化问卷招募受试者。使用逻辑回归确定高血压危机的患病率以及人口统计学和临床因素的关联。

结果

在穆拉戈国家转诊医院急诊病房内科的所有入院患者中,高血压危机的患病率为5.1%(203/4000)。在高血压研究对象中,高血压急症和紧急情况分别占32.5%和67.5%。在患有高血压危机的患者中,41.1%年龄在45 - 65岁之间,一半为女性。与无高血压危机的患者相比,有高血压危机的患者自我报告的依从性存在显著差异,比值比(OR)为52.4(95%置信区间:24.5 - 111.7),p值≤0.001。急性中风是最常见的高血压紧急情况。

结论

高血压紧急情况很常见,且与对规定的抗高血压药物依从性差显著相关。在我们的研究环境中,急性中风是最常见的表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf3a/6531930/3e9099e5c19c/AFHS1901-1757Fig1.jpg

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