Ehsanipoor Robert M, Major Carol A
Johns Hopkins University, Baltimore, Maryland, USA.
Clin Obstet Gynecol. 2011 Jun;54(2):330-6. doi: 10.1097/GRF.0b013e318217d7a6.
Maternal human immunodeficiency virus (HIV) and genital herpes simplex virus (HSV) infection in pregnancy have potential for vertical transmission that may result in death or morbidity. The risk increases with preterm delivery and prolonged ruptured membranes. When managing preterm premature rupture of membranes, the risk of transmission must be weighed against the risk of prematurity. Before 32 to 34 weeks, expectant management is preferred for patients with well controlled HIV or recurrent active genital HSV infection. For patients with advanced HIV disease or primary genital HSV infection, the risk of vertical transmission is higher and many clinical factors need to be considered.
孕期母体感染人类免疫缺陷病毒（HIV）和单纯疱疹病毒（HSV）存在垂直传播的可能性，这可能导致死亡或发病。早产和胎膜早破会增加这种风险。在处理胎膜早破时，必须权衡传播风险与早产风险。在孕32至34周之前，对于HIV病情控制良好或复发性活动性生殖器HSV感染的患者，首选期待疗法。对于患有晚期HIV疾病或原发性生殖器HSV感染的患者，垂直传播风险更高，需要考虑许多临床因素。
