University of Texas Southwestern Medical Center, Dallas, TX, USA.
Pediatr Blood Cancer. 2012 Feb;58(2):303-5. doi: 10.1002/pbc.23148. Epub 2011 Apr 20.
Time-to-antibiotic administration (TTA) has been suggested as a quality-of-care (QOC) measure for pediatric oncology patients with febrile neutropenia (FN). Unknown, however, is to what extent pediatric oncology centers utilize TTA. Therefore, we designed and administered an electronic survey (68% response rate) of programs in the Children's Oncology Group to assess TTA utilization. Nearly half of respondents track TTA. Most reported using a benchmark of less than 60 min from arrival. TTA is a commonly used QOC measure for pediatric FN despite an absence of studies establishing its validity and a lack of data supporting its impact on outcomes of FN.
抗生素给药时间（TTA）已被建议作为儿科肿瘤患者中性粒细胞减少性发热（FN）的护理质量（QOC）指标。然而，目前尚不清楚儿科肿瘤中心在多大程度上利用了 TTA。因此，我们设计并向儿童肿瘤组的计划进行了电子调查（响应率为 68%），以评估 TTA 的利用情况。近一半的受访者跟踪 TTA。大多数人报告使用少于 60 分钟的基准值。尽管缺乏研究证明其有效性，也缺乏数据支持其对 FN 结果的影响，但 TTA 仍是儿科 FN 的常用 QOC 指标。
