Sood Ashwani, Revannasiddaiah Swaroop, Kumar Rakesh
Hell J Nucl Med. 2011 Jan-Apr;14(1):2-5.
We present the different imaging modalities in relation to myeloma, ranging from the time tested X-ray radiography to the newer promising methods of fluorine-18 fluorodesoxyglucose-positron emission tomography ((18)F-FDG-PET) and technetium-99m methoxy isobutyl isonitrite ((99m)Tc-MIBI) scintigraphy. A small discussion regarding newer methods such as fluoride-18 positron emission tomography ((18)F-PET), fluorine-18-fluoro-deoxy-L-thymidine positron emission tomography ((18)F-FLT PET), carbon-11 methionine positron emission tomography ((11)C-methionine PET) and the tritiated thymidine labeling index is also included. They have different mechanisms of tracer uptake enabling the visualization of the spectrum of the disease manifestations ranging from osteoblastic to osteolytic lesions, and also the study of the metabolic status, proliferative and protein activity, in skeletal and in extra-skeletal sites.
我们介绍了与骨髓瘤相关的不同成像方式，从经过时间考验的X线摄影到较新的有前景的方法，如氟-18氟脱氧葡萄糖正电子发射断层扫描（(18)F-FDG-PET）和锝-99m甲氧基异丁基异腈（(99m)Tc-MIBI）闪烁扫描。还对一些较新的方法进行了简短讨论，如氟-18正电子发射断层扫描（(18)F-PET）、氟-18-氟脱氧-L-胸腺嘧啶核苷正电子发射断层扫描（(18)F-FLT PET）、碳-11蛋氨酸正电子发射断层扫描（(11)C-蛋氨酸PET）以及氚标记胸腺嘧啶核苷标记指数。它们具有不同的示踪剂摄取机制，能够显示从成骨病变到溶骨病变的疾病表现谱，还能研究骨骼和骨骼外部位的代谢状态、增殖和蛋白质活性。
