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肾上腺素对大鼠骨骼肌磷酸化酶磷酸酶活性的调控

Control of rat skeletal-muscle phosphorylase phosphatase activity by adrenaline.

作者信息

Tao S H, Huang F L, Lynch A, Glinsmann W H

出版信息

Biochem J. 1978 Oct 15;176(1):347-50. doi: 10.1042/bj1760347.

DOI:10.1042/bj1760347
PMID:215133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1186236/
Abstract

Administration of adrenaline to an isolated rat hindlimb preparation rapidly decreased muscle phosphorylase phosphatase (EC 3.1.3.17) activity and increased heat-stable and trypsin-labile phosphatase inhibitor activity. This was associated with increased tissue cyclic AMP concentrations, phosphorylase (EC 2.4.1.1) activation and glycogen synthase (EC 2.4.1.11) inactivation.

摘要

给离体大鼠后肢标本注射肾上腺素后，肌肉磷酸化酶磷酸酶（EC 3.1.3.17）活性迅速降低，热稳定且对胰蛋白酶敏感的磷酸酶抑制剂活性增加。这与组织环磷酸腺苷浓度升高、磷酸化酶（EC 2.4.1.1）激活及糖原合酶（EC 2.4.1.11）失活有关。

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1
Control of rat skeletal-muscle phosphorylase phosphatase activity by adrenaline.肾上腺素对大鼠骨骼肌磷酸化酶磷酸酶活性的调控
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引用本文的文献

1
Liver phosphorylase phosphatase.肝脏磷酸化酶磷酸酶
Mol Cell Biochem. 1982 Nov 12;49(1):3-15. doi: 10.1007/BF00230991.
2
Phosphorylation of McArdle phosphorylase induces activity.麦卡德尔磷酸化酶的磷酸化可诱导活性。
Proc Natl Acad Sci U S A. 1981 May;78(5):2688-92. doi: 10.1073/pnas.78.5.2688.
3
Adrenal glucocorticoid permissive regulation of muscle glycogenolysis: action on protein phosphatase(s) and its inhibitor(s).肾上腺糖皮质激素对肌肉糖原分解的允许性调节：对蛋白磷酸酶及其抑制剂的作用。
Proc Natl Acad Sci U S A. 1980 Oct;77(10):5711-5. doi: 10.1073/pnas.77.10.5711.
4
Thyrotropin-induced increase in phosphoprotamine phosphatase activity in rat thyroid.促甲状腺素诱导大鼠甲状腺中鱼精蛋白磷酸酶活性增加。
J Endocrinol Invest. 1980 Apr-Jun;3(2):119-23. doi: 10.1007/BF03348237.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
EFFECTS OF ELECTRICAL STIMULATION AND EPINEPHRINE ON MUSCLE PHOSPHORYLASE, PHOSPHORYLASE B KINASE, AND ADENOSINE 3',5'-PHOSPHATE.电刺激和肾上腺素对肌肉磷酸化酶、磷酸化酶B激酶及腺苷3',5'-磷酸的影响
J Biol Chem. 1965 Mar;240:982-5.
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GLYCOGEN SYNTHETASE ACTIVITY IN SKELETAL MUSCLE. INTERCONVERSION OF TWO FORMS AND CONTROL OF GLYCOGEN SYNTHESIS.骨骼肌中的糖原合成酶活性。两种形式的相互转化及糖原合成的调控
J Biol Chem. 1965 Feb;240:588-93.
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Intrinsic regulation of glucose output by rat liver.大鼠肝脏葡萄糖输出的内在调节
Am J Physiol. 1969 Apr;216(4):698-703. doi: 10.1152/ajplegacy.1969.216.4.698.
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A rapid filter paper assay for UDPglucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose.一种用于UDP葡萄糖-糖原葡萄糖基转移酶的快速滤纸测定法，包括改进的UDP-14C-葡萄糖生物合成。
Anal Biochem. 1968 Oct 24;25(1):486-99. doi: 10.1016/0003-2697(68)90127-9.
6
Preparation of tissue extracts for glycogen phosphorylase assay.用于糖原磷酸化酶测定的组织提取物的制备。
Anal Biochem. 1972 May;47(1):28-38. doi: 10.1016/0003-2697(72)90275-8.
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Yeast glycogen synthetase in the glucose 6-phosphate independent form: a case of cold lability without major changes in molecular size.
Biochim Biophys Acta. 1973 Apr 12;302(2):240-8. doi: 10.1016/0005-2744(73)90153-8.
8
Effect of insulin on protein synthesis in skeletal muscle of an isolated perfused preparation of rat hemicorpus.胰岛素对大鼠半侧躯体分离灌注标本骨骼肌中蛋白质合成的影响。
Proc Natl Acad Sci U S A. 1972 Apr;69(4):816-20. doi: 10.1073/pnas.69.4.816.
9
The role of phosphorylase kinase in the nervous and hormonal control of glycogenolysis in muscle.磷酸化酶激酶在肌肉糖原分解的神经和激素控制中的作用。
Biochem Soc Symp. 1974(39):51-73.
10
Activation of phosphorylase phosphatase by a novel procedure: evidence for a regulatory mechanism involving the release of a catalytic subunit from enxyme-inhibitor complex(es) of higher molecular weight.通过一种新方法激活磷酸化酶磷酸酶：关于一种涉及从更高分子量的酶 - 抑制剂复合物中释放催化亚基的调节机制的证据。
Biochem Biophys Res Commun. 1974 Nov 27;61(2):598-604. doi: 10.1016/0006-291x(74)90999-1.