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物质使用障碍患者的创伤后应激障碍、抑郁和自杀倾向。

Post-traumatic stress disorder, depression and suicidality in inpatients with substance use disorders.

机构信息

Northern Sydney Drug and Alcohol Service, Herbert St Clinic, Royal North Shore Hospital, St Leonards, Australia.

出版信息

Drug Alcohol Rev. 2012 May;31(3):294-302. doi: 10.1111/j.1465-3362.2011.00314.x. Epub 2011 Apr 26.

DOI:10.1111/j.1465-3362.2011.00314.x
PMID:21521385
Abstract

INTRODUCTION AND AIMS

The international literature suggests that traumatic events are common for patients with substance use disorders (SUDs), and are often associated with the development of post-traumatic stress disorder (PTSD) and other psychiatric comorbidities. However, limited research has been conducted among Australian SUD patients. The aim of the present study was to examine the prevalence of these disorders in a group of Australian patients admitted for detoxification.

DESIGN AND METHODS

Data were collected from 253 inpatients using a modified version of the Composite International Diagnostic Interview, the 10-item Trauma Screening Questionnaire, the Zung Self-rating Depression Scale and questions from the PsyCheck.

RESULTS

Approximately 20% of inpatients experienced moderate to severe depressive symptoms, and 37% had a lifetime history of self-harm or attempted suicide. Approximately 80% of patients had experienced at least one traumatic event, most experiencing multiple traumas. The mean age of first trauma was 14years. Almost 45% of patients screened positive for current PTSD symptoms. Women were nine times more likely to have been raped and five times more likely to have been sexually molested than men. PTSD symptoms were associated with greater trauma exposure, younger age of first trauma, specific trauma types, moderate to severe depressive symptoms and a history of self-harm or attempted suicide. Despite their difficulties, patients with PTSD symptoms had high rates of retention in treatment.

DISCUSSION AND CONCLUSIONS

Patients entering treatment for SUDs should be assessed for PTSD, depression and suicidality. These conditions impact significantly on treatment outcomes, and require the development of appropriate treatment strategies.

摘要

引言和目的

国际文献表明,创伤事件在物质使用障碍(SUD)患者中很常见,并且常常与创伤后应激障碍(PTSD)和其他精神共病的发展有关。然而,在澳大利亚 SUD 患者中进行的研究有限。本研究的目的是在一组接受解毒治疗的澳大利亚患者中检查这些疾病的患病率。

设计和方法

使用修改后的复合国际诊断访谈、10 项创伤筛查问卷、Zung 自评抑郁量表和 PsyCheck 中的问题,从 253 名住院患者中收集数据。

结果

大约 20%的住院患者有中度至重度抑郁症状,37%有过自残或自杀未遂的病史。大约 80%的患者经历过至少一次创伤事件,大多数患者经历过多次创伤。第一次创伤的平均年龄为 14 岁。近 45%的患者出现当前 PTSD 症状。女性被强奸的可能性是男性的九倍,被性虐待的可能性是男性的五倍。PTSD 症状与更多的创伤暴露、第一次创伤的年龄较小、特定的创伤类型、中重度抑郁症状和自残或自杀未遂的病史有关。尽管他们有困难,但有 PTSD 症状的患者在治疗中保留率很高。

讨论和结论

接受 SUD 治疗的患者应评估 PTSD、抑郁和自杀倾向。这些情况对治疗结果有重大影响,需要制定适当的治疗策略。

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