Chandìa R, Cid E, Vallejos C, Avilas J M
ALFA Instituto de Promoción de la Salud, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile.
Rev Med Chil. 1990 Aug;118(8):855-61.
A disulfiram suspension (propylenglycol and water) was used to treat 45 alcoholic patients. Inactive suspension was given to 8 control alcoholic patients. Pain, local inflammation, thirst and drowsiness were related to disulfiram suspension, but not to solvent administration. Patients receiving disulfiram who drank alcohol experimented the known reaction which was related to subsequent abstinence from alcohol. 67% of patients receiving disulfiram remained abstinent after 1 year of follow up.
使用双硫仑悬浮液（丙二醇和水）治疗45例酒精成瘾患者。给8例对照酒精成瘾患者使用无活性悬浮液。疼痛、局部炎症、口渴和嗜睡与双硫仑悬浮液有关，但与给予溶剂无关。接受双硫仑治疗的患者饮酒后出现了与随后戒酒相关的已知反应。随访1年后，67%接受双硫仑治疗的患者保持戒酒状态。
