Nakudashvili Z K, Mgebrishvili I A, Nakudashvili N K, Mchedlishvili T V, Sanikidze T V
Georgian Med News. 2011 Mar(192):87-92.
The aim of our study was the investigation of toxicity of denture prosthetic appliance Prothyl Hot on the model system of Jurkat cell culture. As a result of our study it was revealed that denture prosthetic appliance Prothyl Hot: - hadn't manifested toxic effects the viability Jurkat cells (that reviled by stability of activity of mitochondrial dehydrogenises and mean of mitochondrial membrane potential; - didn't influence on the balance of pro-and antyinflammatory cytokines, expressed by Jurkat cells; - induces intensification of oxidative metabolism in Jurkat cells, which may be considered as compensatory reaction developing in the cells.
我们研究的目的是在Jurkat细胞培养模型系统中研究义齿修复器具Prothyl Hot的毒性。我们的研究结果表明，义齿修复器具Prothyl Hot：- 未对Jurkat细胞的活力表现出毒性作用（这通过线粒体脱氢酶活性的稳定性和线粒体膜电位平均值得以揭示）；- 未影响Jurkat细胞表达的促炎和抗炎细胞因子的平衡；- 诱导Jurkat细胞氧化代谢增强，这可被视为细胞中发生的代偿反应。
