伊朗糖尿病患者与非糖尿病患者脑血管舒缩反应性的比较。
A comparison of cerebral vasomotor reactivity in diabetic and nondiabetic Iranian patients.
作者信息
Moghaddasi Mehdi, Mamarabadi Mansoureh, Habibi Amir Hosein
机构信息
Assistant Professor of Neurology, Department of Neurology of Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
出版信息
J Res Med Sci. 2010 Jan;15(1):50-3.
BACKGROUND
Cerebral microangiopathy is one of the most important complications in diabetes. It may interfere with cerebral vasomotor reactivity (VMR) which may lead to disability, stroke or even death. The aim of the present study was to determine and compare VMR changes in diabetic and non- diabetic patients.
METHODS
Fifty three diabetic and 51 non- diabetic patients (with no other vascular abnormality) were recruited. Vasomotor reactivity was evaluated with Trans- Cranial Doppler (TCD) before and after CO2 inhalation.
RESULTS
There were 69 (66.30%) males. The mean age was 41.53 ± 17.80 years. The general average of VMR was 5.79 ± 3.00%, the figures in diabetic and nondiabetic patients were 5.31 ± 2.60% and 6.62 ± 2.00%, respectively (p = 0.02). The average of flow velocity (FV) change was 42.47± 29.00 in diabetics and 53.34 ±16.70 in non- diabetic patients (p = 0.04).
CONCLUSIONS
It is recommended that such non- invasive method is necessary for evaluation of cerebral vasculature in diabetic patients for better prevention.
背景
脑微血管病变是糖尿病最重要的并发症之一。它可能会干扰脑血管运动反应性（VMR），进而导致残疾、中风甚至死亡。本研究的目的是确定并比较糖尿病患者和非糖尿病患者的VMR变化。
方法
招募了53例糖尿病患者和51例非糖尿病患者（无其他血管异常）。在吸入二氧化碳前后，使用经颅多普勒（TCD）评估血管运动反应性。
结果
共有69名（66.30%）男性。平均年龄为41.53±17.80岁。VMR的总体平均值为5.79±3.00%，糖尿病患者和非糖尿病患者的数值分别为5.31±2.60%和6.62±2.00%（p = 0.02）。糖尿病患者的血流速度（FV）变化平均值为42.47±29.00，非糖尿病患者为53.34±16.70（p = 0.04）。
结论
建议采用这种非侵入性方法来评估糖尿病患者的脑血管系统，以便更好地进行预防。
Zotero 插件