Venegas F Pablo, Miranda G Gonzalo, Silva C M Consuelo
Unidad de Trastornos del Movimiento, Departamento de Neurología y Neurocirugía, Hospital Clínico Universidad de Chile, Santiago, Chile.
Rev Med Chil. 2011 Jan;139(1):54-9. Epub 2011 Apr 11.
The detection of hyperechogenicity of the substantia nigra using trans cranial sonography can be predictive of the diagnosis of Parkinson Disease.
To report an experience with transcranial sonography for the diagnosis of Parkinson disease. Material ana
One hundred sixteen patients with movement disorders were subjected to a transcranial sonography to detect the presence of hyperechogenicity of the substantia nigra and basal ganglia. Afterwards, two physicians, unaware of the results oft he sonography, examined the patients and reached a clinical diagnosis. The concordance between ultrasound results and the clinical diagnosis was analyzed.
In 64 patients, a clinical diagnosis of Parkinson disease was reached. Of these, 52 patients had substantia nigra hyperechogenicity and in 12, it was normal. On the other hand ultrasound was normal in 42 of 43 patients without a clinical diagnosis of Parkinson disease. Therefore the sensitivity and specificity of trans cranial ultrasound for the diagnosis of Parkinson disease was 81 and 97%, respectively.
Transcranial sonography has a good sensitivity and specificity for the diagnosis of Parkinson disease.
经颅超声检查发现黑质高回声可预测帕金森病的诊断。
报告经颅超声检查诊断帕金森病的经验。材料与方法：对116例运动障碍患者进行经颅超声检查，以检测黑质和基底节是否存在高回声。之后，两名不知超声检查结果的医生对患者进行检查并做出临床诊断。分析超声结果与临床诊断之间的一致性。
64例患者临床诊断为帕金森病。其中，52例患者黑质高回声，12例正常。另一方面，43例未临床诊断为帕金森病的患者中，42例超声检查正常。因此，经颅超声诊断帕金森病的敏感性和特异性分别为81%和97%。
经颅超声对帕金森病的诊断具有良好的敏感性和特异性。
