Department of Surgery, Diyarbakir Education and Research Hospital, 21400, Diyarbakir, Turkey.
World J Gastroenterol. 2011 Apr 21;17(15):1961-70. doi: 10.3748/wjg.v17.i15.1961.
To document unusual findings in appendectomy specimens.
The clinicopathological data of 5262 patients who underwent appendectomies for presumed acute appendicitis from January 2006 to October 2010 were reviewed retrospectively. Appendectomies performed as incidental procedures during some other operation were excluded. We focused on 54 patients who had unusual findings in their appendectomy specimens. We conducted a literature review via the PubMed and Google Scholar databases of English language studies published between 2000 and 2010 on unusual findings in appendectomy specimens.
Unusual findings were determined in 54 (1%) cases by histopathology. Thirty were male and 24 were female with ages ranging from 15 to 84 years (median, 32.2 ± 15.1 years). Final pathology revealed 37 cases of enterobiasis, five cases of carcinoids, four mucinous cystadenomas, two eosinophilic infiltrations, two mucoceles, two tuberculosis, one goblet-cell carcinoid, and one neurogenic hyperplasia. While 52 patients underwent a standard appendectomy, two patients who were diagnosed with tuberculous appendicitis underwent a right hemicolectomy. All tumors were located at the distal part of the appendix with a mean diameter of 6.8 mm (range, 4-10 mm). All patients with tumors were alive and disease-free during a mean follow-up of 17.8 mo. A review of 1366 cases reported in the English literature is also discussed.
Although unusual pathological findings are seldom seen during an appendectomy, all appendectomy specimens should be sent for routine histopathological examination.
记录阑尾切除术标本中的异常发现。
回顾性分析 2006 年 1 月至 2010 年 10 月期间因疑似急性阑尾炎而行阑尾切除术的 5262 例患者的临床病理资料。排除在其他手术中偶然进行的阑尾切除术。我们重点关注 54 例阑尾切除标本中有异常发现的患者。通过 PubMed 和 Google Scholar 数据库，对 2000 年至 2010 年间发表的英文文献中关于阑尾切除标本中异常发现的研究进行了文献回顾。
组织病理学确定 54 例（1%）存在异常发现。男性 30 例，女性 24 例，年龄 15-84 岁（中位数 32.2±15.1 岁）。最终病理显示 37 例为肠虫病，5 例为类癌，4 例为黏液性囊腺瘤，2 例为嗜酸性粒细胞浸润，2 例为黏液囊肿，2 例为结核，1 例为杯状细胞类癌，1 例为神经源性增生。52 例患者行标准阑尾切除术，2 例诊断为结核性阑尾炎行右半结肠切除术。所有肿瘤均位于阑尾远端，平均直径 6.8mm（范围 4-10mm）。所有肿瘤患者在平均 17.8 个月的随访中均存活且无疾病。还讨论了英文文献中报道的 1366 例病例的回顾。
尽管阑尾切除术中很少见到异常的病理发现，但所有阑尾切除标本均应进行常规组织病理学检查。
