Izmir Bozyaka Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Bozyaka, Izmir 35380, Turkey.
Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):247-50. doi: 10.1016/j.archger.2011.03.014. Epub 2011 May 6.
The aim of this retrospective study is to determine the frequency, type, microbiological characteristics and outcome of HAIs in the elderly (age ≥ 65) and to compare the data with younger patients in a Turkish Training and Research Hospital. From January 2008 to December 2009, the infection control team analyzed HAIs among 60,585 hospitalized patients (20,109 aged ≥ 65 and 40,747 aged between 18 and 64 years) with a total number of 419,017 patient days. A total of 825 HAIs episodes were detected in 607 patients, of which 395 episodes were in 301 elderly patients. The incidence of HAIs per 1000 patient days was 2.49 in the elderly and 1.64 in the younger patients' group (p<0.001). The most common site of infection in the elderly patients was the urinary tract, whereas in non-elderly group this was the lower respiratory tract. The incidence density of urinary tract infections, respiratory tract infections, surgical site, skin and soft tissue infections, primary bacteremia, and prosthesis infections were significantly higher in the elderly group (p<0.05). Gram-negative species were the most frequently isolated agents in both groups. There were no significant differences between the groups in the frequency of isolated pathogens or antibiotic susceptibility patterns. Overall, the fatality rate was found 16.8%. The elderly patients were more likely to have crude mortality rates (22% vs. 12%; p<0.01). The death was most often related to pneumonia, primary bacteremia or intravascular catheter infections in both groups.
本回顾性研究旨在确定土耳其一家培训和研究医院中老年人（年龄≥65 岁）医院获得性感染（HAIs）的频率、类型、微生物学特征和结局，并将数据与年轻患者进行比较。2008 年 1 月至 2009 年 12 月，感染控制小组分析了 60585 名住院患者（≥65 岁 20109 人，18-64 岁 40747 人）的 HAI，总患者天数为 419017 天。在 607 名患者中检测到 825 例 HAI 发作，其中 395 例发生在 301 名老年患者中。老年人每 1000 名患者日 HAI 的发病率为 2.49，而年轻患者组为 1.64（p<0.001）。老年患者感染最常见的部位是泌尿道，而非老年组则是下呼吸道。老年人尿路感染、呼吸道感染、手术部位、皮肤和软组织感染、原发性菌血症和假体感染的发病率密度显著更高（p<0.05）。两组均以革兰氏阴性菌为最常分离的病原体。两组间分离病原体的频率或抗生素敏感性模式无显著差异。总的来说，死亡率为 16.8%。老年患者的粗死亡率更高（22% vs. 12%；p<0.01）。两组的死亡最常与肺炎、原发性菌血症或血管内导管感染有关。
