非均匀 B0 和 B1 场中通过分子间双量子相干的高分辨率磁共振波谱。

High-resolution MR spectroscopy via intermolecular double-quantum coherences in inhomogeneous B0 and B1 fields.

机构信息

Department of Electronic Science, Fujian Key Laboratory of Plasma and Magnetic Resonance, State Key Laboratory of Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen, Fujian 361005, P.R. China.

出版信息

Magn Reson Imaging. 2011 Jun;29(5):601-7. doi: 10.1016/j.mri.2011.02.001. Epub 2011 Apr 29.

DOI:10.1016/j.mri.2011.02.001

PMID:21531101

Abstract

Inhomogeneity in static field B0 and/or RF field B1 is inevitable under some circumstances. In this work, a method based on intermolecular double-quantum coherences is employed for high-resolution 1D MR spectroscopy via 2D acquisition under such a condition. High-resolution information on chemical shifts, multiplet patterns, J coupling constants and relative peak areas can be retained in the resulting 1D projected spectra, as shown with results from a narrow-bore NMR spectrometer and a whole-body clinical scanner.

摘要

在某些情况下，静态磁场 B0 和/或射频场 B1 的非均匀性是不可避免的。在这项工作中，我们采用了一种基于分子间双量子相干的方法，在这种情况下通过 2D 采集实现了高分辨率 1D MR 波谱。在得到的 1D 投影谱中，可以保留化学位移、多重峰模式、J 耦合常数和相对峰面积等的高分辨率信息，这一点可以从窄 bore NMR 光谱仪和全身临床扫描仪的结果中得到证明。