Chinese Research Academy of Environmental Sciences, Dayangfang 8, Anwai Beiyuan, Beijing 100012, China.
Chemosphere. 2011 Jun;84(2):241-6. doi: 10.1016/j.chemosphere.2011.04.011. Epub 2011 Apr 30.
Fosfomycin pharmaceutical wastewater contains highly concentrated and refractory antibiotic organic phosphorus (OP) compounds. Wet air oxidation (WAO)-phosphate crystallization process was developed and applied to fosfomycin pharmaceutical wastewater pretreatment and phosphorus recovery. Firstly, WAO was used to transform concentrated and refractory OP substances into inorganic phosphate (IP). At 200°C, 1.0MPa and pH 11.2, 99% total OP (TOP) was transformed into IP and 58% COD was reduced. Subsequently, the WAO effluent was subjected to phosphate crystallization process for phosphorus recovery. At Ca/P molar ratio 2.0:1.0 or Mg/N/P molar ratio 1.1:1.0:1.0, 99.9% phosphate removal and recovery were obtained and the recovered products were proven to be hydroxyapatite and struvite, respectively. After WAO-phosphate crystallization, the BOD/COD ratio of the wastewater increased from 0 to more than 0.5, which was suitable for biological treatment. The WAO-phosphate crystallization process was proven to be an effective method for phosphorus recovery and for fosfomycin pharmaceutical wastewater pretreatment.
磷霉素制药废水中含有高浓度难降解的抗生素有机磷（OP）化合物。开发并应用湿式空气氧化（WAO）-磷酸盐结晶工艺对磷霉素制药废水进行预处理和磷回收。首先，WAO 将浓缩的难降解 OP 物质转化为无机磷酸盐（IP）。在 200°C、1.0MPa 和 pH 11.2 条件下，99%的总 OP（TOP）转化为 IP，同时 COD 去除率为 58%。然后，WAO 出水进行磷酸盐结晶回收磷。当 Ca/P 摩尔比为 2.0:1.0 或 Mg/N/P 摩尔比为 1.1:1.0:1.0 时，磷去除率和回收率分别达到 99.9%，回收产物分别为羟基磷灰石和鸟粪石。WAO-磷酸盐结晶后，废水的 BOD/COD 比值从 0 增加到 0.5 以上，适合生物处理。WAO-磷酸盐结晶工艺是一种有效回收磷和预处理磷霉素制药废水的方法。
