Key Laboratory of Semiconductor Materials Science, Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China.
Spectrochim Acta A Mol Biomol Spectrosc. 2011 Aug;79(3):625-30. doi: 10.1016/j.saa.2011.03.045. Epub 2011 Apr 8.
A sandwich structured substrate was designed for quantitative molecular detection using surface enhanced Raman scattering (SERS), in which the probe molecule was sandwiched between silver nanoparticles (SNPs) and silver nanoarrays. The SNPs was prepared using Lee-Meisel method, and the silver nanoarrays was fabricated on porous anodic aluminum oxide (AAO) using electrodepositing method. The SERS studies show that the sandwich structured substrate exhibits good stability and reproducibility, and the detection sensitivity of Rhodamine 6G (R6G) and Melamine can respectively reach up to 10(-19) M and 10(-9) M, which is improved greatly as compared to other SERS substrates. The improved SERS sensitivity is closely associated with the stronger electromagnetic field enhancement, which stems from localized surface plasmon (LSP) coupling between the two silver nanostructures. Furthermore, the SERS intensity increased almost linearly as the mother concentration increased, which indicates that such a sandwich structure may be used as a good SERS substrate for quantitative analysis.
一种三明治结构的基底被设计用于使用表面增强拉曼散射（SERS）进行定量分子检测，其中探针分子被夹在银纳米粒子（SNPs）和银纳米阵列之间。 SNPs 是使用 Lee-Meisel 方法制备的，而银纳米阵列是使用电化学沉积法在多孔阳极氧化铝（AAO）上制造的。 SERS 研究表明，三明治结构基底具有良好的稳定性和重现性，并且对 Rhodamine 6G（R6G）和三聚氰胺的检测灵敏度分别可达到 10(-19) M 和 10(-9) M，与其他 SERS 基底相比有了很大的提高。 提高的 SERS 灵敏度与更强的电磁场增强密切相关，这源于两种银纳米结构之间的局域表面等离子体（LSP）耦合。 此外，SERS 强度随母体浓度的增加几乎呈线性增加，这表明这种三明治结构可以用作定量分析的良好 SERS 基底。
