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肾移植术后迟发性肺蠊原虫感染:两例报告

Late onset pulmonary Lophomonas blattarum infection in renal transplantation: a report of two cases.

作者信息

He Qiang, Chen Xiuju, Lin Bo, Qu Lihui, Wu Jianyong, Chen Jianghua

机构信息

Kidney Disease Center, First Affiliated Hospital, College of Medicine, Zhejiang University, China.

出版信息

Intern Med. 2011;50(9):1039-43. doi: 10.2169/internalmedicine.50.4672. Epub 2011 May 1.

DOI:10.2169/internalmedicine.50.4672
PMID:21532229
Abstract

Lophomonas blattarum, a rare protozoa, was involved in pulmonary infections of transplant recipients. We report 2 cases of late onset pulmonary L. blattarum infection in renal transplant recipients with normal graft function and relative normal immune function. The diagnosis in both cases was confirmed by bronchoscopy and broncho alveolar lavage (BAL) fluid examination. Both cases were sensitive to metronidazole treatment, but one case did not completely recover during the follow-up. The diagnosis and treatment were discussed to facilitate improvement in the recognition of this rare infection, especially in transplant recipients.

摘要

蜚蠊披发虫是一种罕见的原生动物,可引发移植受者的肺部感染。我们报告2例肾移植受者发生的迟发性肺部蜚蠊披发虫感染,其移植肾功能正常且免疫功能相对正常。两例均经支气管镜检查及支气管肺泡灌洗(BAL)液检查确诊。两例对甲硝唑治疗均敏感,但1例在随访期间未完全康复。对诊断和治疗进行了讨论,以促进对这种罕见感染的认识,尤其是在移植受者中。

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