Gowda Shivaraj, Desai Prakash B, Hull Vinayak V, Math Avinash A K, Vernekar Sonal N, Kulkarni Shruthi S
Dept of Biochemistry, J. N. Medical College, Belgaum 590010. Karnataka. India.
Pan Afr Med J. 2009 Nov 22;3:17.
Laboratory liver tests are broadly defined as tests useful in the evaluation and treatment of patients with hepatic dysfunction. The liver carries out metabolism of carbohydrate, protein and fats. Some of the enzymes and the end products of the metabolic pathway which are very sensitive for the abnormality occurred may be considered as biochemical marker of liver dysfunction. Some of the biochemical markers such as serum bilirubin, alanine amino transferase, aspartate amino transferase, ratio of aminotransferases, alkaline phosphatase, gamma glutamyl transferase, 5' nucleotidase, ceruloplasmin, α-fetoprotein are considered in this article. An isolated or conjugated alteration of biochemical markers of liver damage in patients can challenge the clinicians during the diagnosis of disease related to liver directly or with some other organs. The term "liver chemistry tests" is a frequently used but poorly defined phrase that encompasses the numerous serum chemistries that can be assayed to assess hepatic function and/or injury.
实验室肝脏检查被广泛定义为对肝功能不全患者的评估和治疗有用的检查。肝脏进行碳水化合物、蛋白质和脂肪的代谢。代谢途径中的一些酶和终产物对所发生的异常非常敏感，可被视为肝功能不全的生化标志物。本文考虑了一些生化标志物，如血清胆红素、丙氨酸转氨酶、天冬氨酸转氨酶、转氨酶比值、碱性磷酸酶、γ-谷氨酰转移酶、5'-核苷酸酶、铜蓝蛋白、甲胎蛋白。患者肝脏损伤生化标志物的孤立或结合改变，可在直接诊断与肝脏或其他一些器官相关的疾病时给临床医生带来挑战。“肝脏化学检查”一词是一个常用但定义不明确的短语，涵盖了可用于评估肝功能和/或损伤的众多血清化学检查。
