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Gardasil® - The New HPV Vaccine: The Right Product, the Right Time? A Commentary.加德西®——新型人乳头瘤病毒疫苗:选对产品,恰逢其时?一篇评论
Healthc Policy. 2010 May;5(4):26-36.
2
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An Ethical Justification for Expanding the Notion of Effectiveness in Vaccine Post-Market Monitoring: Insights from the HPV Vaccine in Canada.扩大疫苗上市后监测有效性概念的伦理依据:来自加拿大HPV疫苗的见解
Public Health Ethics. 2016 Apr;9(1):78-91. doi: 10.1093/phe/phu049. Epub 2015 Jan 29.

本文引用的文献

1
ummary of Canadian Immunization Committee (CIC) Recommendations for Human Papillomavirus Immunization Programs.加拿大免疫委员会(CIC)关于人乳头瘤病毒免疫计划的建议摘要。
Can Commun Dis Rep. 2014 Apr 17;40(8):152-153. doi: 10.14745/ccdr.v40i08a02.
2
Postlicensure safety surveillance for quadrivalent human papillomavirus recombinant vaccine.四价人乳头瘤病毒重组疫苗上市后安全性监测
JAMA. 2009 Aug 19;302(7):750-7. doi: 10.1001/jama.2009.1201.
3
Vaccination coverage in 14-year-old adolescents: documentation, timeliness, and sociodemographic determinants.14岁青少年的疫苗接种覆盖率:记录、及时性及社会人口学决定因素
Pediatrics. 2008 Mar;121(3):e428-34. doi: 10.1542/peds.2007-1415.
4
Human papillomavirus (HPV) vaccines: a Canadian update.人乳头瘤病毒(HPV)疫苗:加拿大最新情况
Issues Emerg Health Technol. 2007 Dec(109):1-8.
5
Parental intention to have daughters receive the human papillomavirus vaccine.父母让女儿接种人乳头瘤病毒疫苗的意愿。
CMAJ. 2007 Dec 4;177(12):1506-12. doi: 10.1503/cmaj.071022.
6
Vaccination against human papillomavirus: a baseline survey of Canadian clinicians' knowledge, attitudes and beliefs.人乳头瘤病毒疫苗接种:加拿大临床医生知识、态度和信念的基线调查
Vaccine. 2007 Nov 7;25(45):7841-7. doi: 10.1016/j.vaccine.2007.08.041. Epub 2007 Sep 14.
7
Challenges of implementing human papillomavirus (HPV) vaccination policy.实施人乳头瘤病毒(HPV)疫苗接种政策的挑战。
BMJ. 2007 Aug 25;335(7616):375-7. doi: 10.1136/bmj.39273.458322.BE.
8
Human papillomavirus, vaccines and women's health: questions and cautions.人乳头瘤病毒、疫苗与女性健康:问题与警示
CMAJ. 2007 Aug 28;177(5):484-7. doi: 10.1503/cmaj.070944. Epub 2007 Aug 1.
9
Prophylactic vaccination against human papillomavirus infection and disease in women: a systematic review of randomized controlled trials.女性人乳头瘤病毒感染及疾病的预防性疫苗接种:随机对照试验的系统评价
CMAJ. 2007 Aug 28;177(5):469-79. doi: 10.1503/cmaj.070948. Epub 2007 Aug 1.
10
Process of care failures in invasive cervical cancer: systematic review and meta-analysis.浸润性宫颈癌护理过程中的失败:系统评价与荟萃分析。
Prev Med. 2007 Aug-Sep;45(2-3):93-106. doi: 10.1016/j.ypmed.2007.06.007. Epub 2007 Jun 22.

加德西®——新型人乳头瘤病毒疫苗:选对产品,恰逢其时?一篇评论

Gardasil® - The New HPV Vaccine: The Right Product, the Right Time? A Commentary.

作者信息

Lexchin Joel, Arya Neil, Singh Sonal

机构信息

Professor, School of Health Policy and Management, York University, Emergency Physician, University Health Network.

出版信息

Healthc Policy. 2010 May;5(4):26-36.

PMID:21532767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2875890/
Abstract

The federal and provincial governments have undertaken a universal immunization program to protect school-aged girls against cervical cancer using the new human papillomavirus vaccine Gardasil®. While the vaccine appears to be effective and safe, there are a number of important unanswered questions regarding it and the effects of the immunization program. Here we briefly review key literature about the vaccine and then use the Erickson criteria, which offer an evidence basis for decision-making regarding national immunization strategies, to evaluate whether the program is congruent with sound public health policy. Our analysis of the national decision to recommend and fund a vaccination program using Gardasil® raises significant questions about the basis for this program.

摘要

联邦和省政府已开展一项通用免疫计划,使用新型人乳头瘤病毒疫苗加德西(Gardasil®)来保护学龄女童预防宫颈癌。虽然该疫苗似乎有效且安全,但关于它以及免疫计划的影响仍有许多重要问题尚未得到解答。在此,我们简要回顾关于该疫苗的关键文献,然后运用埃里克森标准(该标准为国家免疫策略的决策提供了证据基础)来评估该计划是否符合合理的公共卫生政策。我们对国家推荐并资助使用加德西(Gardasil®)的疫苗接种计划这一决策的分析,引发了关于该计划依据的重大问题。