Ogilvie Gina S, Remple Valencia P, Marra Fawziah, McNeil Shelly A, Naus Monika, Pielak Karen L, Ehlen Thomas G, Dobson Simon R, Money Deborah M, Patrick David M
University of British Columbia, Vancouver, BC.
CMAJ. 2007 Dec 4;177(12):1506-12. doi: 10.1503/cmaj.071022.
Concerns have been raised that parents may be reluctant to have their daughters receive the human papillomavirus (HPV) vaccine, because of a belief that doing so might be interpreted as condoning earlier and more frequent sexual activity. We determined intentions regarding vaccination among Canadian parents and factors that predicted parental intention to have their daughters vaccinated against HPV.
Parents of children 8-18 years of age, recruited from across Canada, were asked to respond to questions in the context of a grade 6, publicly funded, school-based HPV vaccine program. We performed backward logistic regression analysis to identify factors predictive of parents' intention to have their daughters vaccinated against HPV.
Of the 1350 respondents with female children, more than 70% (73.8%; 95% confidence interval [CI] 71.5%-76.1%) intended to have their daughters undergo vaccination against HPV. In multivariable modelling, parents who had positive attitudes toward vaccines (odds ratio [OR] 9.9, 95% CI 4.7-21.1), those who were influenced by subjective norms (OR 9.2, 95% CI 6.6-12.9), those who felt that the vaccine had limited influence on sexual behaviour (OR 3.2, 95% CI 2.2-4.6) and those who thought someone they knew was likely to get cervical cancer (OR 1.5, 95% CI 1.1-2.1) were more likely to intend that their daughters receive the HPV vaccine. Parents who were older (v. younger) (OR 0.6, 95% CI 0.4-0.8) and those who resided in British Columbia or Yukon Territory (v. Atlantic Canada) (OR 0.5, 95% CI 0.3-0.9) were less likely to intend that their daughters receive the HPV vaccine.
Most of the parents surveyed intended that their daughters would receive vaccination against HPV. Overall attitudes toward vaccines in general and toward the HPV vaccine in particular constituted the most significant predictor of parental intention with regard to vaccination.
有人担心父母可能不愿让女儿接种人乳头瘤病毒(HPV)疫苗,因为他们认为这样做可能被解读为纵容更早及更频繁的性行为。我们确定了加拿大父母关于疫苗接种的意向以及预测父母让女儿接种HPV疫苗意向的因素。
从加拿大各地招募8至18岁儿童的父母,要求他们在六年级由公共资金资助的基于学校的HPV疫苗接种计划背景下回答问题。我们进行了向后逻辑回归分析,以确定预测父母让女儿接种HPV疫苗意向的因素。
在1350名有女儿的受访者中,超过70%(73.8%;95%置信区间[CI]71.5%-76.1%)打算让女儿接种HPV疫苗。在多变量建模中,对疫苗持积极态度的父母(优势比[OR]9.9,95%CI 4.7-21.1)、受主观规范影响的父母(OR 9.2,95%CI 6.6-12.9)、认为疫苗对性行为影响有限的父母(OR 3.2,95%CI 2.2-4.6)以及认为他们认识的人可能患宫颈癌的父母(OR 1.5,95%CI 1.1-2.1)更有可能打算让女儿接种HPV疫苗。年龄较大(与较年轻相比)的父母(OR 0.6,95%CI 0.4-0.8)以及居住在不列颠哥伦比亚省或育空地区(与加拿大大西洋省份相比)的父母(OR 0.5,95%CI 0.3-0.9)不太可能打算让女儿接种HPV疫苗。
大多数接受调查的父母打算让女儿接种HPV疫苗。总体而言,对疫苗尤其是对HPV疫苗的态度是父母疫苗接种意向的最重要预测因素。