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机械瓣膜置换术后患者的孕期随访:在撒哈拉以南非洲地区可行吗?

Pregnancy follow-up in a patient with mechanical valve: possible in sub-Saharan Africa?

作者信息

Tchoumi Jacques Cabral Tantchou, Ambassa Jean Claude, Butera Gianfranco

机构信息

Shisong Cardiac Centre, Kumbo, Cameroon.

出版信息

Pan Afr Med J. 2009 Mar 6;2:1.

Abstract

BACKGROUND

In Africa in general and in Cameroon in particular, post rheumatic cardiopathies are a health care problem, one of the causes of infertility in the women population and a major cause of death among children and adults. Management of a pregnant woman with mechanical heart valve is a complex issue for all health care providers involved in the care of such patients.

PATIENT AND CASE REPORT

Miss A is 26-years old and consulted for cardiac assessment; referred from Bamenda (North-West province of Cameroon) for better management of a cardiac problem including arrhythmia and a history of recurrent tonsillitis. The cardiac echo-dopplerography showed severe post-rheumatic mitral valve regurgitation with pulmonary hypertension and a dysfunctional left ventricle. The patient was later evacuated in a surgical centre in Milan San Donato (Italy) where a St. Jude mechanical heart valve N.27 was implanted. Two years after surgery, during a follow-up visit, the patient brought a pelvic ultrasound showing a single live intrauterine foetus, gestational age estimated at 7 weeks.

CONCLUSION

Management of mechanical valve in a pregnancy context, resulting in a favourable outcome (no thromboembolic events and the delivery of a healthy baby) is possible in sub-Saharan Africa. Close observation, adherence to existing clinical guidelines, patient cooperation and an appropriate technical infrastructure are critical factors to consider.

摘要

背景

总体而言在非洲,尤其是在喀麦隆,风湿性心脏病后遗症是一个医疗保健问题,是女性人群不孕的原因之一,也是儿童和成人死亡的主要原因。对于所有参与此类患者护理的医疗保健提供者来说,管理患有机械心脏瓣膜的孕妇是一个复杂的问题。

患者及病例报告

A小姐26岁,因心脏评估前来就诊;从喀麦隆西北部的巴门达转诊而来,以便更好地管理包括心律失常和复发性扁桃体炎病史在内的心脏问题。心脏超声多普勒检查显示严重的风湿性二尖瓣反流伴肺动脉高压和左心室功能障碍。该患者后来被转移到意大利米兰圣多纳托的一个外科中心,在那里植入了一枚型号为27的圣犹达机械心脏瓣膜。手术后两年,在一次随访中,患者带来了一份盆腔超声检查报告,显示宫内有一个单活胎,估计孕周为7周。

结论

在撒哈拉以南非洲,在妊娠情况下管理机械瓣膜并取得良好结果(无血栓栓塞事件且分娩出健康婴儿)是可能的。密切观察、遵守现有临床指南、患者合作以及适当的技术基础设施是需要考虑的关键因素。

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本文引用的文献

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Anticoagulation during pregnancy.孕期抗凝治疗。
Curr Womens Health Rep. 2002 Apr;2(2):95-104.
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Anticoagulants in pregnancy.孕期抗凝剂
Br Heart J. 1995 Aug;74(2):107-11. doi: 10.1136/hrt.74.2.107.

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