Department of Medical Psychology and Sociology, University of Leipzig, Leipzig, Germany.
Eur J Cancer Care (Engl). 2011 Sep;20(5):601-9. doi: 10.1111/j.1365-2354.2011.01256.x. Epub 2011 Apr 28.
The assessment of quality of life in cancer patients is hampered because patients may change their frames of reference during the course of the disease. The aim of this study was to test individual differences in these response shift effects. Urologic cancer patients (n= 275) were examined during the stay in the hospital (T1), 2 weeks later (T2) and 3 months later (T3). Furthermore, at T3 they were asked to retrospectively assess their situation at T1 (then-test). The difference between this retrospective assessment and the original assessment at T1 was used to determine the response shift effect (recalibration). Anxiety (Generalized Anxiety Disorder Questionnaire-2), depression (Patient Health Questionnaire-2) and health dissatisfaction (Questionnaire on Life Satisfaction) were obtained at all points in time. The effect sizes of the mean response shift effects (recalibration) ranged between 0.26 and 0.48. Nevertheless, a large proportion of the sample showed no response shift (22-38%) or even negative response shift effects (20-30%). There were significant correlations among the response shift measures of the domains (anxiety, depression and health dissatisfaction) with coefficients between 0.29 and 0.51. The results indicate that response shift should not only be assessed on the mean score level, since it is also a dimension of individual difference.
癌症患者生活质量的评估受到阻碍，因为患者在疾病过程中可能会改变参考框架。本研究旨在测试这些反应转移效应的个体差异。泌尿科癌症患者（n=275）在住院期间（T1）、2 周后（T2）和 3 个月后（T3）进行了检查。此外，在 T3 时，他们被要求回顾性评估他们在 T1 时的情况（回溯测试）。将回溯评估与 T1 时的原始评估之间的差异用于确定反应转移效应（校准）。在所有时间点都获得了焦虑（广泛性焦虑障碍问卷-2）、抑郁（患者健康问卷-2）和健康不满（生活满意度问卷）。平均反应转移效应（校准）的效应量介于 0.26 和 0.48 之间。然而，很大一部分样本没有反应转移（22-38%），甚至出现负反应转移效应（20-30%）。各领域（焦虑、抑郁和健康不满）的反应转移测量之间存在显著相关性，系数介于 0.29 和 0.51 之间。结果表明，反应转移不应仅在平均得分水平上进行评估，因为它也是个体差异的一个维度。
