Bøgevig Søren, Høgberg Lotte Christine Groth, Dalhoff Kim Peder, Mortensen Ole Steen
Department of Anaesthesiology, Bispebjerg Hospital, Bispebjerg Bakke 23, Copenhagen NV, Denmark.
Dan Med Bull. 2011 May;58(5):A4268.
The Danish Poison Information Centre (DPIC) provides information to the public and health care professionals on acute poisonings. The DPIC received 41,000 enquiries during the first three years of its existence as an open 24h telephone service. The aim of this data register study was to classify all substance exposures, to gain knowledge of the status and trends in poisonings (toxico-surveillance) and to evaluate the development in the number of contacts.
Information and inquiries were continuously entered into a poison-centre database. A new classification system was established during the study to ensure that all agents were properly classified. A total of 41,139 calls were divided into 18 substance categories, each consisting of 3-11 subgroups.
The number of contacts per year increased by 70% from 2007 to 2009. Three contacts per thousand individuals in the Danish population were registered in 2009. For all groups, except drugs of abuse, the data showed an increase in the actual number of exposures from 2008 to 2009. Pharmaceuticals represent one third of substance exposures, and analgesics constitute a third of these poisonings. A relative increase in contacts concerning household substances, plants and vitamins was observed.
The classification gave detailed knowledge of the current poisoning status. Evaluation of subgroups showed a need for a larger number of subgroups to ensure a sufficient level of toxico-surveillance. Compared to other national poison centres, we predict a doubling in enquiries during the next ten years, mainly from the public.
丹麦毒物信息中心（DPIC）向公众和医疗保健专业人员提供有关急性中毒的信息。作为一个24小时开放的电话服务机构，DPIC在成立的头三年共收到41000次咨询。本数据登记研究的目的是对所有物质暴露进行分类，了解中毒的现状和趋势（毒物监测），并评估联系次数的变化。
信息和咨询不断录入毒物中心数据库。在研究期间建立了一个新的分类系统，以确保所有制剂都能得到正确分类。总共41139个电话被分为18个物质类别，每个类别由3 - 11个子组组成。
从2007年到2009年，每年的联系次数增加了70%。2009年丹麦人口中每千人有三次联系被记录。对于所有类别，除了滥用药物外，数据显示从2008年到2009年实际暴露次数有所增加。药品占物质暴露的三分之一，其中镇痛药占这些中毒事件的三分之一。观察到与家用物质、植物和维生素有关的联系次数相对增加。
该分类提供了当前中毒状况的详细信息。对亚组的评估表明需要更多的亚组以确保足够水平的毒物监测。与其他国家毒物中心相比，我们预计在未来十年咨询次数将翻倍，主要来自公众。
