Universidade Estadual Paulista, Presidente Prudente, SP, Brazil.
Arq Bras Cardiol. 2011 Jun;96(6):465-70. doi: 10.1590/s0066-782x2011005000050. Epub 2011 Apr 29.
Obesity is linked to high blood pressure (HBP) in childhood. However, the role of fat as a predictor of HBP in adolescents remains unknown.
To investigate the association between general and abdominal obesity with HBP and to identify the sensitivity and specificity of these indicators to detect HBP in adolescents.
The sample was composed of 1,021 adolescents aged 10-17 years. Subjects were classified as normal, overweight/obese, according to BMI measurements, and as non-obese and with abdominal obesity, according to waist circumference (WC) measurements. Systolic (SBP) and diastolic (DBP) blood pressure were assessed using an oscillometric device. Logistic regression and ROC curves were used in the statistical analysis.
The overall prevalence of HBP was 11.8% (13.4% in boys and 10.2% in girls). The prevalence of HBP among general overweight/obese boys and girls was 10% and 11.1%, respectively. The prevalence of HBP among boys with abdominal obesity was 28.6%. For both genders, the odds ratio (OR) for HBP was higher in abdominal obesity than in general overweight/obesity (4.09 [OR(95%CI) = 2.57-6.51]) versus 1.83 [OR(95%CI) = 1.83-4.30]). The OR for HBP was higher when general overweight/obesity and abdominal obesity were clustered (OR = 4.35 [OR(95%CI) = 2.68-7.05]), than when identified by either general overweight/obesity or abdominal obesity alone (OR = 1.32 [OR(95%CI) = 0.65-2.68]). However, both types of obesity had low predictive power in HBP detection.
General and abdominal obesity were associated to HBP, however, the sensitivity and specificity of these variables to detect HBP are low in Brazilian adolescents.
肥胖与儿童期高血压（HBP）有关。然而，脂肪作为青少年 HBP 的预测因子的作用尚不清楚。
研究一般肥胖和腹型肥胖与 HBP 的关系，并确定这些指标检测青少年 HBP 的敏感性和特异性。
样本由 1021 名 10-17 岁的青少年组成。根据 BMI 测量结果将受试者分为正常体重/超重和肥胖，根据腰围（WC）测量结果将受试者分为非肥胖和腹型肥胖。使用振荡法测量收缩压（SBP）和舒张压（DBP）。统计学分析采用逻辑回归和 ROC 曲线。
HBP 的总体患病率为 11.8%（男孩为 13.4%，女孩为 10.2%）。一般超重/肥胖男孩和女孩中 HBP 的患病率分别为 10%和 11.1%。腹型肥胖男孩中 HBP 的患病率为 28.6%。对于两种性别，腹型肥胖的 HBP 比值比（OR）均高于一般超重/肥胖（4.09 [OR（95%CI）= 2.57-6.51] 比 1.83 [OR（95%CI）= 1.83-4.30]）。当一般超重/肥胖和腹型肥胖同时存在时，HBP 的 OR 更高（OR = 4.35 [OR（95%CI）= 2.68-7.05]），而当仅存在一般超重/肥胖或腹型肥胖时，OR 较低（OR = 1.32 [OR（95%CI）= 0.65-2.68]）。然而，这两种类型的肥胖在检测 HBP 方面的预测能力都较低。
一般肥胖和腹型肥胖与 HBP 相关，但这些变量检测 HBP 的敏感性和特异性在巴西青少年中较低。
