Casebolt D B, Leary S L, Undeutsch L
Department of Comparative Medicine, University of Alabama, Birmingham 35294.
Lab Anim Sci. 1990 Jan;40(1):65-7.
To test whether exposure to dichlorvos vapors for treatment of mouse ectoparasites resulted in temporary cessation of breeding, we exposed harem breeding groups of mice to varying concentrations of dichlorvos vapors and examined the effects of exposure on litter frequency and litter size. All exposure levels resulted in decreased plasma cholinesterase concentrations in treated mice for up to 10 days following the completion of exposure. Litter frequency and size were unaffected by dichlorvos exposure, and gestation times were not prolonged. Therefore, treatment with dichlorvos vapors during breeding did not affect reproduction in exposed mice.
为了测试将敌敌畏蒸汽用于治疗小鼠体外寄生虫是否会导致繁殖暂时停止，我们将多雌多雄制繁殖组的小鼠暴露于不同浓度的敌敌畏蒸汽中，并研究暴露对产仔频率和窝仔数的影响。在暴露结束后的长达10天内，所有暴露水平均导致受试小鼠血浆胆碱酯酶浓度降低。产仔频率和窝仔数不受敌敌畏暴露的影响，妊娠期也未延长。因此，在繁殖期间用敌敌畏蒸汽处理不会影响暴露小鼠的繁殖。
