Department of Anesthesiology & Critical Care Medicine, George Washington University Medical Center, Washington DC 20037, USA.
Pain Med. 2011 Jun;12(6):864-70. doi: 10.1111/j.1526-4637.2011.01119.x. Epub 2011 May 3.
To evaluate the relationship between commonly used final needle-tip positions and subsequent contrast flow and patient-reported pain relief in transforaminal epidural steroid injections (TFESIs).
Retrospective cross-sectional study.
Medical records of subjects (N = 83) having undergone a TFESI between January 2008 and January 2009 were reviewed to compare TFESIs using the superior-anterior (SA) vs. the superior-posterior (SP) quadrant.
Outcome measures included ventral and dorsal epidural contrast flow as well as near-to-complete pain relief as measured by numerical rating scale pain score pre- and post-procedure.
SA TFESIs were associated with greater ventral epidural contrast flow as compared with SP TFESIs (100% vs 61.4%, P < 0.001). SA TFESIs with ventral epidural contrast flow were also associated with flow to a greater number of vertebral levels than SP TFESIs with ventral epidural contrast flow (41% vs 14.8%, P < 0.001). SP TFESIs were associated with greater dorsal epidural contrast flow than SA TFESIs (95.5% vs 43.6%, P < 0.05). SA TFESIs were also associated with a larger proportion of patients who achieved near-to-complete pain relief (P < 0.05) and greater reduction than SP TFESIs in post-procedure pain score relative to pre-procedure (3.3 vs 1.5, P < 0.01).
The evolution of TFESIs must balance both safety and efficacy. The efficacy of SA TFESIs is demonstrated to be superior to that of SP TFESIs with regards to ventral epidural flow and patient-reported pain relief. Further efforts should focus on demonstrating efficacy while optimizing safety.
评估经椎间孔硬膜外类固醇注射(TFESI)中常用的最终针尖位置与随后的对比流动和患者报告的疼痛缓解之间的关系。
回顾性横截面研究。
回顾性分析 2008 年 1 月至 2009 年 1 月期间接受 TFESI 的患者的病历,比较使用前上-前(SA)与前上-后(SP)象限的 TFESI。
与 SP TFESI 相比,SA TFESI 与更大的腹侧硬膜外对比流动相关(100%比 61.4%,P<0.001)。具有腹侧硬膜外对比流动的 SA TFESI 也与比具有腹侧硬膜外对比流动的 SP TFESI 更多的椎体水平的流动相关(41%比 14.8%,P<0.001)。SP TFESI 与比 SA TFESI 更大的背侧硬膜外对比流动相关(95.5%比 43.6%,P<0.05)。SA TFESI 也与更大比例的患者达到接近完全的疼痛缓解相关(P<0.05),与 SP TFESI 相比,术后疼痛评分的降低更大(3.3 比 1.5,P<0.01)。
TFESI 的演变必须平衡安全性和疗效。与 SP TFESI 相比,SA TFESI 的腹侧硬膜外流动和患者报告的疼痛缓解效果更好。进一步的努力应侧重于在优化安全性的同时提高疗效。