Parikh Mitul, Samujh Ram, Kanojia Ravi P, Mishra Anand Kumar, Sodhi Kushaljit Singh, Bal Amanjit
Department of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Chang Gung Med J. 2011 Mar-Apr;34(2):213-7.
Peripheral primitive neuroectodermal tumor of the chest wall is a rare malignant tumor usually occurring in children. The tumor shares a similar histology, immunohistology and cytogenetics to Ewing's sarcoma. The location of the tumor in the chest wall poses a major challenge with respect to the diagnostic workup and treatment which involves multidisciplinary management. Neoadjuvant chemotherapy is given initially and is followed by complete surgical resectioning of the mass followed by repeat chemotherapy with or without radiotherapy. We report a case of peripheral primitive neuroectodermal tumor of the chest wall in a 5-year-old boy and review the literature regarding its diagnosis and management.
胸壁外周原始神经外胚层肿瘤是一种罕见的恶性肿瘤，通常发生于儿童。该肿瘤在组织学、免疫组织学和细胞遗传学方面与尤因肉瘤相似。肿瘤位于胸壁给诊断检查和治疗带来了重大挑战，治疗需要多学科管理。最初给予新辅助化疗，随后对肿块进行完整的手术切除，之后根据情况进行重复化疗，可联合或不联合放疗。我们报告一例5岁男孩的胸壁外周原始神经外胚层肿瘤病例，并复习其诊断和治疗的相关文献。
