Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taipei, Taiwan.
J Formos Med Assoc. 2011 Apr;110(4):230-8. doi: 10.1016/S0929-6646(11)60035-1.
BACKGROUND/PURPOSE: People receive electrocardiogram (ECG) examination for various reasons in a hospital setting. An important clinical practice issue may be that cardiologists need to be consulted for Brugada-type ECGs identified through routine screening. We investigated the prevalence and prognosis of patients with Brugada-type ECG in a hospital-based population in an attempt to improve the management of these patients.
In 20,562 patients seeking medical care for non-cardiovascular reasons, 74,955 ECGs were performed from December 1999 to February 2001. The diagnostic criteria for Brugada-like ECG from the European Society of Cardiology were used. International Statistical Classification of Diseases codes and city residents' records were documented to indicate the reasons for visiting clinics or hospitalization and mortality outcome. Medical records were reviewed and telephone interviews were conducted.
Twenty-six (0.13%) of the 20,562 patients were confirmed to have Brugada-type ECGs. None of these patients had ever experienced syncope, near syncope or sudden cardiac death. After 57.1 ± 15.8 months of follow-up, there were four deaths out of the 26 patients with Brugada-type ECG (15.4%, 95% CI: 1.53-2.9%) compared with 2899 of those without (14.1%, 95% CI: 13.6-14.5%; p=0.89, log-rank test). Neither sudden cardiac death (p=0.61) nor hospitalized death (p=0.55) was different between patients with and without Brugada-type ECG.
Patients with Brugada-type ECGs are not rare in a hospital-based population. The presence of Brugada-type ECGs in patients without syncope or sudden cardiac death was not associated with hospitalized mortality.
背景/目的：在医院环境中，人们出于各种原因接受心电图（ECG）检查。一个重要的临床实践问题可能是，通过常规筛查发现 Brugada 型 ECG 后需要咨询心脏病专家。我们调查了医院人群中 Brugada 型 ECG 患者的患病率和预后，试图改善这些患者的管理。
在 20562 名因非心血管原因寻求医疗的患者中，从 1999 年 12 月至 2001 年 2 月进行了 74955 次心电图检查。使用欧洲心脏病学会的 Brugada 样心电图诊断标准。记录国际疾病分类代码和城市居民记录，以表明就诊或住院的原因和死亡率结果。审查了病历并进行了电话访谈。
20562 例患者中确诊 26 例（0.13%）为 Brugada 型 ECG。这些患者均无晕厥、近乎晕厥或心源性猝死史。随访 57.1±15.8 个月后，26 例 Brugada 型 ECG 患者中有 4 例死亡（15.4%，95%CI：1.53-2.9%），而 2899 例无 Brugada 型 ECG 患者中有 2899 例死亡（14.1%，95%CI：13.6-14.5%；p=0.89，对数秩检验）。Brugada 型 ECG 患者与无 Brugada 型 ECG 患者的心脏性猝死（p=0.61）或住院死亡（p=0.55）无差异。
在医院人群中，Brugada 型 ECG 患者并不少见。无晕厥或心源性猝死患者存在 Brugada 型 ECG 与住院死亡率无关。
