Department of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA.
Chem Commun (Camb). 2011 Jul 14;47(26):7464-6. doi: 10.1039/c1cc11951f. Epub 2011 May 4.
Engineered enzyme conjugate of the small laccase enzyme from Streptomyces coelicolor and zinc finger DNA binding domain from Zif268 is demonstrated to bind double stranded DNA in a site specific manner while retaining enzymatic activity.
工程酶缀合物由链霉菌中的小漆酶和 Zif268 的锌指 DNA 结合结构域组成,该缀合物被证明能够以特定方式结合双链 DNA,同时保持酶活性。