Department of Radiology, and Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Korea.
Cardiovasc Intervent Radiol. 2012 Apr;35(2):292-8. doi: 10.1007/s00270-011-0162-6. Epub 2011 May 4.
This study was designed to evaluate the clinical efficacy and safety of transcatheter arterial embolization (TAE) with n-butyl cyanoacrylate (NBCA) for intramuscular active hemorrhage of varied etiologies and anatomic sites.
Eighteen patients who demonstrated hematoma with pseudoaneurysm and/or active extravasation of contrast media underwent TAE with NBCA. Etiologies of hematoma included trauma, postoperative complication, and coagulopathy (due to underlying disease or anticoagulation therapy). Sites of embolization included chest wall, abdomen wall, retroperitoneum, and extremity. TAE was performed by using 1:3 to 1:5 mixtures of NBCA and iodized oil, either solely (n = 15) or in combination with microcoil (n = 3). The technical and clinical success rate, procedure-related complications, and clinical outcomes were evaluated.
The technical and clinical success rates were 100% and 83% (15/18), respectively. Two patients expired while admitted due to other comorbidities. One patient expired due to recurrent bleeding at another site. There were no serious complications relating to the embolization procedure.
TAE with NBCA is effective and safe treatment modality for intramuscular active hemorrhage.
本研究旨在评估 n-丁基氰基丙烯酸酯（NBCA）经导管动脉栓塞（TAE）治疗多种病因和解剖部位肌内活动性出血的临床疗效和安全性。
18 例患者表现为血肿伴假性动脉瘤和/或造影剂外渗，行 NBCA TAE。血肿病因包括外伤、术后并发症和凝血功能障碍（由基础疾病或抗凝治疗引起）。栓塞部位包括胸壁、腹壁、腹膜后和四肢。采用 1:3 至 1:5 的 NBCA 与碘油混合物进行 TAE，单独使用（n=15）或与微线圈联合使用（n=3）。评估技术和临床成功率、与操作相关的并发症和临床结果。
技术和临床成功率分别为 100%和 83%（15/18）。2 例患者因其他合并症住院期间死亡。1 例患者因另一部位再次出血而死亡。无与栓塞术相关的严重并发症。
NBCA 经导管动脉栓塞术是治疗肌内活动性出血的有效且安全的治疗方法。
