Won Y, Lee S L, Kim Y, Ku Y M
Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Diagn Interv Imaging. 2015 Jun;96(6):563-9. doi: 10.1016/j.diii.2015.01.003. Epub 2015 Feb 14.
Transcatheter endovascular embolization within a reasonable time before rupture or deterioration of a patient's general condition is an important procedure for managing visceral pseudoaneurysms. N-butyl 2-cyanoacrylate (NBCA, enbucrilate) is an embolic material used in the blockade of visceral pseudoaneurysms. This study evaluated the clinical efficacy of transcatheter embolization of visceral artery pseudoaneurysms using NBCA.
Between June 2004 and February 2014, 13 patients (9 males and 4 females; age range, 26-80years; mean, 57.9years) with 14 pseudoaneurysms were treated by transcatheter embolization using NBCA. NBCA was mixed with iodized oil at a 1:3 ratio to control its polymerization time and to render it radiopaque. Pseudoaneurysms were located on the gastroduodenal artery (n=1), pancreaticoduodenal artery (n=2), dorsal pancreatic artery (n=1), proximal jejunal artery (n=1), colic artery (n=1), splenic artery (n=3), renal artery (n=4; two in one patient), and hepatic artery (n=1).
All patients recovered immediately following the embolization procedure, and two patients showed minor complications that required only medical observation.
Transcatheter embolization using NBCA for the treatment of visceral pseudoaneurysms is a safe, effective, and low-cost treatment method with a high success rate.
在患者全身状况出现破裂或恶化之前的合理时间内进行经导管血管内栓塞术是处理内脏假性动脉瘤的重要方法。正丁基-2-氰基丙烯酸酯(NBCA,恩布酯)是一种用于封堵内脏假性动脉瘤的栓塞材料。本研究评估了使用NBCA经导管栓塞内脏动脉假性动脉瘤的临床疗效。
2004年6月至2014年2月期间,13例患者(9例男性,4例女性;年龄范围26 - 80岁,平均57.9岁)共14个假性动脉瘤接受了使用NBCA的经导管栓塞治疗。NBCA与碘化油按1:3的比例混合,以控制其聚合时间并使其具有放射性不透明性。假性动脉瘤位于胃十二指肠动脉(1例)、胰十二指肠动脉(2例)、胰背动脉(1例)、空肠近端动脉(1例)、结肠动脉(1例)、脾动脉(3例)、肾动脉(4例;1例患者有2个)和肝动脉(1例)。
所有患者在栓塞术后立即康复,2例患者出现轻微并发症,仅需医学观察。
使用NBCA经导管栓塞治疗内脏假性动脉瘤是一种安全、有效且低成本的治疗方法,成功率高。