高剂量阿立哌唑致吞咽困难。
High dosage of aripiprazole-induced dysphagia.
机构信息
Department of Psychiatry, Lu-Tung Branch of Changhua Christian Hospital, LuKang, Taiwan.
出版信息
Int J Eat Disord. 2012 Mar;45(2):305-6. doi: 10.1002/eat.20934. Epub 2011 May 3.
BACKGROUND
Dysphagia as a main manifestation of extrapyramidal symptoms is an uncommon adverse effect of second-generation antipsychotics.
METHOD
We present a 54-year-old drug-naïve patient with schizophrenia, who developed dysphagia with aripiprazole 30 mg daily treatment.
RESULTS
This is the first case report on aripiprazole-induced dysphagia. We discuss the risk factors that led to dysphagia in this case.
CONCLUSION
Aripiprazole-induced dysphagia is rare, and it is important to be aware that it does occur with high-dosage treatment.
背景
以延髓外症状为主要表现的吞咽困难是第二代抗精神病药物的一种罕见不良反应。
方法
我们报告了一例 54 岁、未曾用药的精神分裂症患者，每日服用阿立哌唑 30mg 后出现吞咽困难。
结果
这是首例阿立哌唑致吞咽困难的病例报告。我们讨论了导致该病例吞咽困难的风险因素。
结论
阿立哌唑引起的吞咽困难较为罕见，但需要注意的是，高剂量治疗时确实会发生这种情况。
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