Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, 130022, P. R. China.
Chemistry. 2011 Jun 14;17(25):7013-9. doi: 10.1002/chem.201100202. Epub 2011 May 3.
Single-walled carbon nanotubes (SWNTs) have received much attention in nanotechnology because of their potential applications in molecular electronics, field-emission devices, biomedical engineering, and biosensors. Carbon nanotubes as gene and drug delivery vectors or as "building blocks" in nano-/microelectronic devices has been successfully explored. However, since SWNTs lack chemical recognition, SWNT-based electronic devices and sensors are strictly related to the development of a bottom-up self-assembly technique. Here we present an example of using DNA duplex-based protons (H(+)) as a fuel to control reversible assembly of SWNTs without generation of waste duplex products that poison DNA-based systems.
单壁碳纳米管（SWNTs）在纳米技术中受到了广泛关注，因为它们在分子电子学、场发射器件、生物医学工程和生物传感器等领域具有潜在的应用。碳纳米管作为基因和药物输送载体，或者作为纳米/微电子器件中的“构建块”，已经得到了成功的探索。然而，由于 SWNTs 缺乏化学识别，因此基于 SWNTs 的电子器件和传感器与开发自下而上的自组装技术密切相关。在这里，我们展示了一个例子，即使用基于 DNA 双链体的质子（H(+）作为燃料，来控制 SWNTs 的可逆组装，而不会产生毒害基于 DNA 的系统的废双链体产物。
