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小分子化合物诱导干细胞分化的应用

[Application of small molecule compounds inducing differentiation of stem cells].

作者信息

Li Xia, Shan Lei, Li Wen-lin, Zhang Shou-de, Zhang Wei-dong

机构信息

Department of Medicinal Chemistry of Natural Product, School of Pharmacy, Second Military Medical University, Shanghai 200433, China.

出版信息

Yao Xue Xue Bao. 2011 Feb;46(2):121-6.

Abstract

With the development of stem cells and regenerative medicine (treatment of various diseases using stem cells) research, the induction of differentiation of human stem cell technology has also made significant progress. The development of chemical biology offers a variety of small biological molecules for stem cell biology. This review focuses on how small molecule compounds (natural and synthetic) induce differentiation of stem cells.

摘要

随着干细胞和再生医学(利用干细胞治疗各种疾病)研究的发展,人类干细胞技术的诱导分化也取得了重大进展。化学生物学的发展为干细胞生物学提供了多种小生物分子。本综述重点关注小分子化合物(天然和合成的)如何诱导干细胞分化。

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