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用于检测细微活动受限的简易评估工具的开发:日常使用的技术是否可以区分 MCI 和阿尔茨海默病?

Development of a short-form assessment for detection of subtle activity limitations: can use of everyday technology distinguish between MCI and Alzheimer's disease?

机构信息

Division of Occupational Therapy, 23200, Department of Neurobiology, Care Science and Society, Karolinska Institutet, 141 83 Huddinge, Sweden.

出版信息

Expert Rev Neurother. 2011 May;11(5):647-55. doi: 10.1586/ern.11.55.

Abstract

Research demonstrates that people with mild cognitive impairment (MCI) do have limitations in instrumental activities of daily living, social and other complex activities, but there is still a lack of knowledge on how such functional limitations are best detected and evaluated in the heterogeneous MCI population. In general, existing functional assessments lack sufficient sensitivity to detect subtle changes or differences in this population. Therefore, further development of valid, up-to-date, sensitive assessments is needed. Interestingly, activities that involve the use of everyday technology (e.g., using telephone or household equipment, managing finances and transportation) have demonstrated the best sensitivity to detect differences between people with MCI, people with early-stage dementia and controls. This article introduces the development of assessments of the ability to use everyday technology, and presents empirical material describing the procedures of developing the Short-form Everyday Technology Use Questionnaire (S-ETUQ), a screening tool that distinguishes MCI from controls and Alzheimer's disease, intended to complement other functional assessments.

摘要

研究表明,轻度认知障碍(MCI)患者在工具性日常生活活动、社交和其他复杂活动方面确实存在局限性,但对于如何在异质的 MCI 人群中最好地检测和评估这些功能局限性,仍缺乏了解。一般来说,现有的功能评估缺乏足够的敏感性来检测该人群中的细微变化或差异。因此,需要进一步开发有效、最新和敏感的评估方法。有趣的是,涉及使用日常技术的活动(例如,使用电话或家庭设备、管理财务和交通)已被证明对检测 MCI 患者、早期痴呆患者和对照组之间的差异具有最佳敏感性。本文介绍了日常技术使用能力评估的开发,并介绍了描述开发短期日常技术使用问卷(S-ETUQ)的程序的实证材料,这是一种筛选工具,可将 MCI 与对照组和阿尔茨海默病区分开来,旨在补充其他功能评估。

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