Academic Department of Trauma and Orthopaedic Surgery, Leeds NIHR Biomedical Research Unit, Clarendon Wing, Floor A, Great George Street, Leeds General Infirmary, Leeds LS1 3EX, UK.
Injury. 2011 Jun;42(6):591-8. doi: 10.1016/j.injury.2011.03.036. Epub 2011 May 4.
Reconstruction of diaphyseal bone defects still represents a major clinical challenge. Several approaches are used with the common objective to regenerate bone loss and restore function. The methods most commonly used are the vascularised fibula autograft and the Ilizarov bone transfer technique. Recently, Masquelet proposed a procedure combining induced membranes and cancellous autografts. The aim of this article was to briefly describe the technique, to review the current evidence and to discuss the tips and tricks that could help the surgeons to improve outcome. Future directions to increase its effectiveness and expand its application are also being discussed. However, predicting the outcome of reconstruction of bone defects remains difficult; and the patient should always be informed that, although potential complications are mostly predictable, in most of the cases the reconstruction process is long and difficult.
骨干骨缺损的重建仍然是一个主要的临床挑战。目前有几种方法被用于共同的目标，即再生骨丢失和恢复功能。最常用的方法是带血管腓骨自体移植和伊利扎洛夫骨转移技术。最近，Masquelet 提出了一种结合诱导膜和松质骨自体移植的方法。本文的目的是简要描述该技术，回顾目前的证据，并讨论有助于外科医生提高疗效的技巧。还讨论了增加其有效性和扩大其应用的未来方向。然而，预测骨缺损重建的结果仍然很困难；并且患者应该始终被告知，尽管潜在的并发症大多是可预测的，但在大多数情况下，重建过程是漫长而困难的。
