Department of Orthopedics, Guangdong Second Provincial General Hospital, No.466 Xingang Zhong Road, Guangzhou, China.
J Orthop Surg Res. 2024 Sep 28;19(1):600. doi: 10.1186/s13018-024-05093-0.
The induced membrane technique (IMT) is a two-step procedure used for reconstructing segmental bone defects in the limbs. The osteogenic mechanism after bone grafting using IMT remains unclear, and efforts to modify the original techniques are limited to the investigative phase. Therefore, reviewing existing knowledge and identifying hotspots and new trends in IMT is critical.
We retrieved reviews and articles associated with IMT published between 2004 and 2023 from the Web of Science Core Collection (WoSCC). The keywords included induced membrane technique, guided bone regeneration, bone defect reconstruction, bone graft, stem cells, Masquelet technique, management of bone defects, and scaffold. HistCite, VOSviewer, CiteSpace, and R-bibliometrics were used for scientometric analysis.
A total of 1019 publications from 374 academic journals with 33,995 co-cited references by 2,331 institutions from 65 countries or regions were included. China (n = 235) and the United States (n = 215) were the most productive countries, with Shanghai Jiao Tong University producing the most number of publications (n = 18). Journal Injury [co-citations = 1774; impact factor (IF) 2022 = 2.5] published the most manuscripts, while Masquelet AC and Giannoudis PV published literature with a significant influence on IMT, showing more co-citations (n = 727; n = 355). Two preface hotspots of IMT focused on investigating the microscopic mechanism (such as the membrane supporting graft-to-bone union and the role of inflammatory cells) and developing new techniques to improve IMT (such as bone tissue engineering and new drugs).
This study comprehensively reviewed the literature about IMT published in the last 20 years using qualitative and quantitative methods, providing valuable information for researchers investigating IMT.
诱导膜技术（IMT）是一种两步法，用于重建四肢的节段性骨缺损。使用 IMT 进行植骨后的成骨机制尚不清楚，对原始技术的改进努力仅限于研究阶段。因此，回顾现有知识并确定 IMT 的热点和新趋势至关重要。
我们从 Web of Science 核心合集（WoSCC）中检索了 2004 年至 2023 年期间发表的与 IMT 相关的综述和文章。关键词包括诱导膜技术、引导骨再生、骨缺损重建、骨移植物、干细胞、Masquelet 技术、骨缺损管理和支架。使用 HistCite、VOSviewer、CiteSpace 和 R-bibliometrics 进行科学计量分析。
共纳入来自 374 种学术期刊的 1019 篇出版物，来自 65 个国家或地区的 2331 个机构的 33995 次共被引，中国（n=235）和美国（n=215）是最具生产力的国家，上海交通大学发表的论文数量最多（n=18）。期刊 Injury [共被引 1774 次；2022 年影响因子（IF）2.5] 发表的论文最多，而 Masquelet AC 和 Giannoudis PV 发表的文献对 IMT 有重大影响，共被引次数更多（n=727；n=355）。IMT 的两个前序热点集中在研究微观机制（如膜支撑移植物与骨的结合和炎症细胞的作用）和开发新技术以改进 IMT（如骨组织工程和新药）。
本研究使用定性和定量方法全面回顾了过去 20 年发表的关于 IMT 的文献，为研究 IMT 的研究人员提供了有价值的信息。
