Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Germany.
Brief Bioinform. 2011 May;12(3):253-8. doi: 10.1093/bib/bbq074.
Validation of genetic associations is understood to be a cornerstone for the scientific credibility of the results. To approach this topic, the general concept of genetic association studies is introduced briefly, followed by how the term 'validation' is used in the context of genetic association studies. As a central issue, reasons for the importance of validation and for failure of validation will be described.
验证遗传关联被认为是科学可信度的基石。为了探讨这个主题，简要介绍了遗传关联研究的一般概念，然后介绍了“验证”一词在遗传关联研究中的用法。作为一个核心问题，将描述验证的重要性以及验证失败的原因。
