Kovac Jason R, Flood Diane, Mullen J Brendan, Fischer Marc Anthony
McMaster Institute of Urology, St Joseph's Hospital, 50 Charlton Ave E, Hamilton, Ontario L8N 4A6, Canada.
J Androl. 2012 Mar-Apr;33(2):162-6. doi: 10.2164/jandrol.110.012534. Epub 2011 May 5.
Genitourinary sarcoidosis is uncommon, with only rare documented cases of testicular involvement reported. We detail the case of a 37-year-old male who initially presented for azoospermia and secondary infertility. A testicular biopsy revealed nonnecrotizing granulomas and a chest x-ray identified perihilar lymphadenopathy and granulomatous lung nodules. A corticosteroid regimen was administered, and routine semen analyses were conducted. Significant improvements were noted after prednisone treatments. A successful in vivo fertilization was obtained. This is the first known case of testicular sarcoidosis diagnosed during investigations into azoospermia and secondary infertility which, after treatment with corticosteroids, resulted in natural fertilization.
泌尿生殖系统结节病并不常见，仅有罕见的睾丸受累病例报道。我们详细介绍了一名37岁男性的病例，该患者最初因无精子症和继发性不孕前来就诊。睾丸活检显示非坏死性肉芽肿，胸部X光检查发现肺门周围淋巴结肿大和肉芽肿性肺结节。给予了皮质类固醇治疗方案，并进行了常规精液分析。泼尼松治疗后有显著改善。成功实现了体内受精。这是已知的首例在无精子症和继发性不孕调查期间诊断出的睾丸结节病病例，经皮质类固醇治疗后自然受孕。
