Sheikh Imran, Kanwal Ayesha, Kyprianou Annette
Department of Medicine, Case Western Reserve University School of Medicine at MetroHealth Medical Center, Cleveland, OH, USA.
JOP. 2011 May 6;12(3):247-9.
While the majority of acute pancreatitis is secondary to alcohol and gallstones in the developed world, infectious causes are recognized and recent evidence has linked influenza A to acute pancreatitis.
We report a patient with acute pancreatitis deemed secondary to influenza B virus; however considering this would be the first reported case, retesting showed that the initial PCR was falsely positive and a system-wide contamination discovered that unearthed other false negatives.
While research must continue to describe novel infectious etiologies of acute pancreatitis, caution must be exercised before new associations are described. New tests are leading to increasing incidence and prevalence of disease and while such testing generally has high sensitivity and specificity, the role for false results still exists.
在发达国家，大多数急性胰腺炎继发于酒精和胆结石，但感染性病因也得到认可，最近有证据表明甲型流感与急性胰腺炎有关。
我们报告了一例被认为继发于乙型流感病毒的急性胰腺炎患者；然而，鉴于这将是首例报告病例，重新检测显示最初的聚合酶链反应（PCR）结果为假阳性，并且全系统污染的发现揭示了其他假阴性结果。
虽然必须继续开展研究以描述急性胰腺炎新的感染性病因，但在描述新的关联之前必须谨慎。新的检测方法导致疾病的发病率和患病率不断上升，虽然此类检测通常具有高灵敏度和特异性，但假结果的情况仍然存在。
