Uden D J P van, Ullmann E F, Reijnen M M P J
Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands.
J Cancer Res Ther. 2011 Jan-Mar;7(1):75-7. doi: 10.4103/0973-1482.80472.
Only a limited group of patients with non-small-cell lung cancer (NSCLC) is eligible for treatment with a curative intent. Adrenalectomy for a solitary adrenal metastasis of NSCLC may be curative when combined with resection of the primary tumor. It is unclear whether resection of an isolated adrenal metastasis is justified in patients with a second metastasis. We report a case of successful adrenalectomy with adjuvant chemotherapy in a patient who was previously treated with a right lower lobe resection and subsequent Gamma Knife treatment of an intracranial metastasis. At 20-month follow-up, patient was in a good clinical condition without signs of recurrent disease. In selected cases, adrenalectomy with adjuvant chemotherapy for an adrenal metastasis of NSCLC may be performed successfully, with good short-term results, even after earlier treatment of a cerebral metastasis.
只有一小部分非小细胞肺癌（NSCLC）患者适合接受根治性治疗。对于NSCLC孤立性肾上腺转移患者，肾上腺切除术联合原发性肿瘤切除可能具有治愈效果。对于存在第二种转移的患者，切除孤立性肾上腺转移瘤是否合理尚不清楚。我们报告了一例患者，该患者先前接受了右下叶切除术，随后对颅内转移瘤进行了伽玛刀治疗，之后成功进行了肾上腺切除术并接受了辅助化疗。在20个月的随访中，患者临床状况良好，无疾病复发迹象。在某些特定病例中，即使在先前已对脑转移瘤进行治疗的情况下，对NSCLC肾上腺转移瘤进行肾上腺切除术并辅助化疗仍可能成功进行，且短期效果良好。
