Department of Pediatrics and Communicable Diseases, University of Michigan Health System, Ann Arbor, MI, USA.
J Perinatol. 2012 Jan;32(1):51-4. doi: 10.1038/jp.2011.50. Epub 2011 May 5.
We evaluated the effect of late preterm delivery (34 to 36 weeks) on hospital mortality of infants with congenital heart defects (CHDs).
Retrospective record review of infants with major CHD born at or after to 34 weeks, cared for in a single tertiary perinatal center between 2002 and 2009. Factors associated with death before discharge from the hospital were ascertained using univariate and multivariate analyses.
Of the 753 infants with CHD, 117 were born at late preterm. Using logistic regression analysis, white race (OR; 95% CI) (0.60; 0.39 to 0.95), late preterm delivery (2.70; 1.69 to 4.33), and need for intubation in the delivery room (3.15; 1.92 to 5.17) were independently associated with hospital death.
Late preterm birth of infants with major CHDs was independently associated with increased risk of hospital death compared with delivery at more mature gestational ages.
评估 34 至 36 孕周晚期早产儿出生对先天性心脏病（CHD）患儿院内死亡率的影响。
对 2002 年至 2009 年间在一家三级围产期中心出生的胎龄≥34 周且患有重大 CHD 的婴儿进行回顾性病历回顾。采用单因素和多因素分析确定出院前死亡的相关因素。
在 753 例患有 CHD 的婴儿中，有 117 例出生于晚期早产儿。使用逻辑回归分析，白人种族（比值比；95%可信区间）（0.60；0.39 至 0.95）、晚期早产儿分娩（2.70；1.69 至 4.33）和分娩室需要插管（3.15；1.92 至 5.17）与院内死亡独立相关。
与在更成熟的胎龄分娩相比，患有重大 CHD 的晚期早产儿出生与院内死亡风险增加独立相关。
