Klein Carsten, Lang Ute, Bükki Johannes, Sittl Reinhard, Ostgathe Christoph
Division of Palliative Medicine, University of Erlangen, Germany.
Breast Care (Basel). 2011;6(1):27-34. doi: 10.1159/000324702. Epub 2011 Feb 22.
Patients with advanced life-limiting disease often suffer from symptoms that considerably impair their quality of life and that of their families. Palliative care aims to alleviate these symptoms by a multidimensional approach. Pharmacotherapy is an essential component. The objective of this review is to give an overview of symptom-oriented drug therapy for the most important symptoms in palliative care. Leading symptoms that affect quality of life include pain, dyspnea, nausea and emesis, weakness and disorientation. Careful examination and history taking help to understand the individual mechanisms underlying these symptoms. Specific pharmacotherapy provides an efficient way to achieve symptom control in the context of palliative care.
患有晚期绝症的患者常常遭受严重影响其自身及家人生活质量的症状困扰。姑息治疗旨在通过多维度方法缓解这些症状。药物治疗是其中的重要组成部分。本综述的目的是概述姑息治疗中针对最重要症状的症状导向性药物治疗。影响生活质量的主要症状包括疼痛、呼吸困难、恶心呕吐、虚弱和意识障碍。仔细的检查和病史采集有助于了解这些症状背后的个体机制。在姑息治疗背景下，特定的药物治疗为实现症状控制提供了一种有效的方法。
